Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing

Autor: Su Ling, M Riising Eva, Gamba Cristina, Blondal Thorarinn, Szabova Ludmila, Mouritzen Peter, Jagd Lea Møller, M Johnston Camille, J Mikkelsen Marie, Wu Xiaolin, Demirov Dimiter, Guo Shuang

Publikováno v: Methods

Validation of CRISPR-Cas9 editing typically explores the immediate vicinity of the gene editing site and distal off-target sequences, which has led to the conclusion that CRISPR-Cas9 editing is very specific. However, an increasing number of studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3c80cda0b5a4acb008e5f809a135ac

Verification of CRISPR editing and finding transgenic inserts by Xdrop™ Indirect sequence capture followed by short- and long- read sequencing

Autor: Gamba Cristina, Guo Shuang, Marie Just Mikkelsen, Su Ling, Blondal Thorarinn, Camille M. Johnston, Eva M. Riising, Wu Xiaolin, Demirov Dimiter, Mouritzen Peter, Jagd Lea Møller, Szabova Ludmila

Validation of CRISPR-Cas9 editing typically explore the immediate vicinity of the gene editing site and distal off-target sequences, which have led to the conclusion that CRISPR-Cas9 editing is very specific. However, an increasing number of studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::99094df4e091123f2791a2b41c235614
https://doi.org/10.1101/2020.05.28.105718

The prognostic value of microRNA-126 and microvessel density in patients with stage II colon cancer

Autor: Hansen, Torben Frøstrup, Kjær-Frifeldt, Sanne, Morgenthaler, Søren, Blondal, Thorarinn, Lindebjerg, Jan, Jakobsen, Anders, Sørensen, Flemming Brandt

Publikováno v: Hansen, T F, Kjær-Frifeldt, S, Morgenthaler, S, Blondal, T, Lindebjerg, J, Jakobsen, A & Sørensen, F B 2014, ' The prognostic value of microRNA-126 and microvessel density in patients with stage II colon cancer ', Journal of Translational Medicine, bind 12 . https://doi.org/10.1186/s12967-014-0254-6

BACKGROUND: Angiogenesis plays a pivotal role in malignant tumour growth and the metastatic process. We analysed the prognostic value of two angiogenesis parameters, microRNA-126 (miRNA-126) and microvessel density (MVD), in a population based cohort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::5e6d0bc58f6759670ae3e5b841607260
https://pure.au.dk/portal/da/publications/the-prognostic-value-of-microrna126-and-microvessel-density-in-patients-with-stage-ii-colon-cancer(f0fd62c6-2670-42c8-a620-4d8300032008).html

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