STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

Autor: Ramadhin AR; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Lee SH; Division of Biochemistry, Netherlands Cancer Institute and Oncode Institute, 1066 CX Amsterdam, the Netherlands., Zhou D; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Salmazo A; Institute of Science and Technology Austria (ISTA), 3400 Klosterneuburg, Austria., Gonzalo-Hansen C; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., van Sluis M; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Blom CMA; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Janssens RC; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Raams A; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Dekkers D; Proteomics Center, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Bezstarosti K; Proteomics Center, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Slade D; Department of Medical Biochemistry, Medical University of Vienna, Max Perutz Labs, Vienna Biocenter, 1030 Vienna, Austria., Vermeulen W; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Pines A; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Demmers JAA; Proteomics Center, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands., Bernecky C; Institute of Science and Technology Austria (ISTA), 3400 Klosterneuburg, Austria., Sixma TK; Division of Biochemistry, Netherlands Cancer Institute and Oncode Institute, 1066 CX Amsterdam, the Netherlands. Electronic address: t.sixma@nki.nl., Marteijn JA; Department of Molecular Genetics, Oncode Institute, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CN Rotterdam, the Netherlands. Electronic address: j.marteijn@erasmusmc.nl.

Publikováno v: Molecular cell [Mol Cell] 2024 Dec 19; Vol. 84 (24), pp. 4740-4757.e12. Date of Electronic Publication: 2024 Nov 14.