Výsledky vyhledávání - "Bloks, Niek GC"

Akademický článek

A Damaging COL6A3 Variant Alters the MIR31HG‐Regulated Response of Chondrocytes in Neocartilage Organoids to Hyperphysiologic Mechanical Loading.

Autor: Bloks, Niek GC¹ (AUTHOR), Harissa, Zainab^2,3 (AUTHOR), Mazzini, Giorgia¹ (AUTHOR), Adkar, Shaunak S^2,3 (AUTHOR), Dicks, Amanda R^2,3 (AUTHOR), Hajmousa, Ghazaleh¹ (AUTHOR), Steward, Nancy^2,3 (AUTHOR), Koning, Roman I.¹ (AUTHOR), Mulder, Aat¹ (AUTHOR), de Koning, Berend B.R.¹ (AUTHOR), Kloppenburg, Margreet¹ (AUTHOR), de Almeida, Rodrigo Coutinho¹ (AUTHOR), Ramos, Yolande FM¹ (AUTHOR), Guilak, Farshid^2,3 (AUTHOR), Meulenbelt, Ingrid¹ (AUTHOR) i.meulenbelt@lumc.nl

Publikováno v: Advanced Science. 9/25/2024, Vol. 11 Issue 36, p1-15. 15p.

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Hyper-physiologic mechanical cues, as an osteoarthritis disease relevant environmental perturbation, cause a critical shift in set-points of methylation at transcriptionally active CpG sites in neo-cartilage organoids.

Autor: Bloks NG; Leiden University Medical Center., Dicks A; Washington University in St. Louis., Harissa Z; Washington University in St. Louis., Nelissen RG; Leiden University Medical Center., Hajmousa G; Leiden University Medical Center., Ramos YF; Leiden University Medical Center., Almeida RC; Leiden University Medical Center., Guilak F; Washington University in St. Louis., Meulenbelt I; Leiden University Medical Center.

Publikováno v: Research square [Res Sq] 2023 Nov 15. Date of Electronic Publication: 2023 Nov 15.

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