Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Blischak P"'
OmicNavigator: open-source software for the exploration, visualization, and archival of omic studies
Autor:
Terrence R. Ernst, John D. Blischak, Paul Nordlund, Joe Dalen, Justin Moore, Akshay Bhamidipati, Pankaj Dwivedi, Joe LoGrasso, Marco Rocha Curado, Brett Warren Engelmann
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The results of high-throughput biology (‘omic’) experiments provide insight into biological mechanisms but can be challenging to explore, archive and share. The scale of these challenges continues to grow as omic research volu
Externí odkaz:
https://doaj.org/article/da5c781ee7424b5d975e1ed6e5bb02cd
Akademický článek
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Autor:
Lauren E. Blake, Samantha M. Thomas, John D. Blischak, Chiaowen Joyce Hsiao, Claudia Chavarria, Marsha Myrthil, Yoav Gilad, Bryan J. Pavlovic
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background There is substantial interest in the evolutionary forces that shaped the regulatory framework in early human development. Progress in this area has been slow because it is difficult to obtain relevant biological samples. Induced p
Externí odkaz:
https://doaj.org/article/dd38d81b30244cec9b99740c49443fe0
Akademický článek
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Autor:
John D. Blischak, Ludovic Tailleux, Marsha Myrthil, Cécile Charlois, Emmanuel Bergot, Aurélien Dinh, Gloria Morizot, Olivia Chény, Cassandre Von Platen, Jean-Louis Herrmann, Roland Brosch, Luis B. Barreiro, Yoav Gilad
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Tuberculosis (TB) is a deadly infectious disease, which kills millions of people every year. The causative pathogen, Mycobacterium tuberculosis (MTB), is estimated to have infected up to a third of the world’s population; however, only app
Externí odkaz:
https://doaj.org/article/ffefa45ee3b3462d9dbdbe1fa3f7f223
Publikováno v:
F1000Research, Vol 8 (2019)
Making scientific analyses reproducible, well documented, and easily shareable is crucial to maximizing their impact and ensuring that others can build on them. However, accomplishing these goals is not easy, requiring careful attention to organizati
Externí odkaz:
https://doaj.org/article/1e789e14047d4ad080773629aae125af
Publikováno v:
Applications in Plant Sciences, Vol 7, Iss 8, Pp n/a-n/a (2019)
Premise Environmentally controlled facilities, such as growth chambers, are essential tools for experimental research. Automated, low‐cost, remote‐monitoring hardware can greatly improve both reproducibility and maintenance. Methods and Results U
Externí odkaz:
https://doaj.org/article/50ef9bffaadb4558b338a617ce30c31e
Autor:
Abhishek K Sarkar, Po-Yuan Tung, John D Blischak, Jonathan E Burnett, Yang I Li, Matthew Stephens, Yoav Gilad
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008045 (2019)
Quantification of gene expression levels at the single cell level has revealed that gene expression can vary substantially even across a population of homogeneous cells. However, it is currently unclear what genomic features control variation in gene
Externí odkaz:
https://doaj.org/article/3ceae214409c455fb8382e3025a6c93b
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 5, Pp 1345-1355 (2016)
The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), plays an important immunomodulatory role, regulating transcription of genes in the innate and adaptive immune system. The present study examines patterns of transcriptome-wide response t
Externí odkaz:
https://doaj.org/article/9c09026c70ea41799f46da46a8c28350
Autor:
David A Knowles, Courtney K Burrows, John D Blischak, Kristen M Patterson, Daniel J Serie, Nadine Norton, Carole Ober, Jonathan K Pritchard, Yoav Gilad
Publikováno v:
eLife, Vol 7 (2018)
Anthracycline-induced cardiotoxicity (ACT) is a key limiting factor in setting optimal chemotherapy regimes, with almost half of patients expected to develop congestive heart failure given high doses. However, the genetic basis of sensitivity to anth
Externí odkaz:
https://doaj.org/article/ae37104e044f44d5aa898ec315db662b