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1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT 6 R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity.

Autor: Canale V; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland., Trybała W; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland., Chaumont-Dubel S; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Koczurkiewicz-Adamczyk P; Department of Pharmaceutical Biochemisty, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland., Satała G; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Krakow, Poland., Bento O; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France.; IBMM, Université de Montpellier, CNRS, ENSCM, 34095 Montpellier, France., Blicharz-Futera K; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland., Bantreil X; IBMM, Université de Montpellier, CNRS, ENSCM, 34095 Montpellier, France.; Institut Universitaire de France (IUF), 75005 Paris, France., Pękala E; Department of Pharmaceutical Biochemisty, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland., Bojarski AJ; Department of Medicinal Chemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smętna Street, 31-343 Krakow, Poland., Lamaty F; IBMM, Université de Montpellier, CNRS, ENSCM, 34095 Montpellier, France., Marin P; Institut de Génomique Fonctionelle, Université de Montpellier, CNRS, INSERM, 34094 Montpellier, France., Zajdel P; Department of Organic Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland.

Publikováno v: Biomolecules [Biomolecules] 2022 Dec 21; Vol. 13 (1). Date of Electronic Publication: 2022 Dec 21.