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Autor:
Gilan, O, Lam, EYN, Becher, I, Lugo, D, Cannizzaro, E, Joberty, G, Ward, A, Wiese, M, Fong, CY, Ftouni, S, Tyler, D, Stanley, K, MacPherson, L, Weng, C-F, Chan, Y-C, Ghisi, M, Smil, D, Carpenter, C, Brown, P, Garton, N, Blewitt, ME, Bannister, AJ, Kouzarides, T, Huntly, BJP, Johnstone, RW, Drewes, G, Dawson, S-J, Arrowsmith, CH, Grandi, P, Prinjha, RK, Dawson, MA
Targeted therapies against disruptor of telomeric silencing 1-like (DOT1L) and bromodomain-containing protein 4 (BRD4) are currently being evaluated in clinical trials. However, the mechanisms by which BRD4 and DOT1L regulate leukemogenic transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd41bdeee106695c6be2455010c50f8f
Autor:
Gocuk SA; Department of Optometry and Vision Sciences, The University of Melbourne, Parkville Victoria 3010, Australia.; Centre for Eye Research Australia, East Melbourne, Victoria 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria 3010, Australia., Lancaster J; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Su S; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia., Jolly JK; Vision and Eye Research Institute, Anglia Ruskin University, Cambridge CB1 2LZ, United Kingdom., Edwards TL; Centre for Eye Research Australia, East Melbourne, Victoria 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria 3010, Australia., Hickey DG; Centre for Eye Research Australia, East Melbourne, Victoria 3002, Australia., Ritchie ME; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia., Blewitt ME; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia., Ayton LN; Department of Optometry and Vision Sciences, The University of Melbourne, Parkville Victoria 3010, Australia.; Centre for Eye Research Australia, East Melbourne, Victoria 3002, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, Melbourne, Victoria 3010, Australia., Gouil Q; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; gouil.q@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Publikováno v:
Genome research [Genome Res] 2024 Nov 20; Vol. 34 (11), pp. 1954-1965. Date of Electronic Publication: 2024 Nov 20.
Autor:
Bennett C; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Pettikiriarachchi A; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., McLean ARD; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia., Harding R; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Blewitt ME; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Epigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Seillet C; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Pasricha SR; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.; Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, Victoria, Australia.; Clinical Haematology at the Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Publikováno v:
American journal of hematology [Am J Hematol] 2024 Nov; Vol. 99 (11), pp. 2075-2083. Date of Electronic Publication: 2024 Aug 17.
Autor:
Short KM, Tortelote GG, Jones LK, Diniz F, Edgington-Giordano F, Cullen-McEwen LA, Schröder J, Spencer A, Keniry A, Polo JM, Bertram JF, Blewitt ME, Smyth IM, El-Dahr SS
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 19. Date of Electronic Publication: 2024 Aug 19.
Autor:
Tan W, Park JV, Venugopal H, Lou JQ, Dias PS, Baldoni PL, Dite T, Moon KW, Keenan CR, Gurzau AD, Leis A, Yousef J, Vaibhav V, Dagley LF, Ang CS, Corso L, Davidovich C, Vervoort SJ, Smyth GK, Blewitt ME, Allan RS, Hinde E, D'Arcy S, Ryu JK, Shakeel S
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 28. Date of Electronic Publication: 2024 Jun 28.
Autor:
Keenan CR; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia; keenanc@unimelb.edu.au rallan@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Coughlan HD; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Iannarella N; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia., Tapia Del Fierro A; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Keniry A; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Johanson TM; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Chan WF; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Garnham AL; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Whitehead LW; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Blewitt ME; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.; School of Mathematics and Statistics, The University of Melbourne, Parkville, Victoria, 3010, Australia., Allan RS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia; keenanc@unimelb.edu.au rallan@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Publikováno v:
Genome research [Genome Res] 2024 May 15; Vol. 34 (4), pp. 556-571. Date of Electronic Publication: 2024 May 15.
Autor:
Bergamasco MI; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Vanyai HK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Garnham AL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Geoghegan ND; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Vogel AP; Centre for Neurosciences of Speech, University of Melbourne, Parkville, Victoria, Australia.; Redenlab Inc., Melbourne, Australia., Eccles S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Rogers KL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; School of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia., Blewitt ME; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Hannan AJ; Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, Victoria, Australia., Thomas T; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and., Voss AK; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology and.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2024 Apr 01; Vol. 134 (7). Date of Electronic Publication: 2024 Apr 01.