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pro vyhledávání: '"Blessing D. Deeyaa"'
Publikováno v:
Bioconjug Chem
Polyamine and polyammonium ion conjugates are often used to direct reagents to nucleic acids based on their strong electrostatic attraction to the phosphoribose backbone. Such non-specific interactions do not typically alter the specificity of the at
Autor:
Steven E. Rokita, Blessing D. Deeyaa
Publikováno v:
Organic & Biomolecular Chemistry. 18:1671-1678
The dynamic nature of nucleic acid alkylation by simple ortho quinone methides (QM) and their conjugates has provided numerous opportunities ranging from sequence selective targeting to bipedal walking in duplex DNA. To enhance the diffusion rate of