Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Blessing Bassey-Archibong"'
Autor:
Chu Shiun Lo, Sara Ibrahim Omar, Jinlan Chang, Blessing Bassey-Archibong, Jack A Tuszynski, Nadia Jahroudi, Manijeh Pasdar
Publikováno v:
Re:GEN Open, Vol 3, Iss 1, Pp 40-51 (2023)
Background: The conformational p53-R175H is the most frequently occurring p53 mutant in cancers and a focus of mutant p53 targeted therapies. Plakoglobin is a dual cell adhesion and signaling protein with tumor suppressor activity. We previously show
Externí odkaz:
https://doaj.org/article/bd71a0ad83ac407888f30f165dbb77bf
Autor:
Branavan Manoranjan, Chitra Venugopal, David Bakhshinyan, Ashley A. Adile, Laura Richards, Michelle M. Kameda-Smith, Owen Whitley, Anna Dvorkin-Gheva, Minomi Subapanditha, Neil Savage, Nazanin Tatari, Dillon McKenna, Blessing Bassey-Archibong, Neil Winegarden, Robin Hallett, John P. Provias, Blake Yarascavitch, Olufemi Ajani, Adam Fleming, Gary D. Bader, Trevor J. Pugh, Bradley W. Doble, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The Wnt molecular subgroup of medulloblastoma is associated with better prognosis than the other molecular subgroups. Here, the authors show that activating Wnt signaling impairs tumor development and improves survival in Group 3 and Group 4 medullob
Externí odkaz:
https://doaj.org/article/90b86d3d0f9c41078f2e0a70337929d5
Autor:
Max A. K. Rätze, Thijs Koorman, Thijmen Sijnesael, Blessing Bassey-Archibong, Robert van de Ven, Lotte Enserink, Daan Visser, Sridevi Jaksani, Ignacio Viciano, Elvira R. M. Bakker, François Richard, Andrew Tutt, Lynda O’Leary, Amanda Fitzpatrick, Pere Roca-Cusachs, Paul J. van Diest, Christine Desmedt, Juliet M. Daniel, Clare M. Isacke, Patrick W. B. Derksen
Publikováno v:
Oncogene. 41:3507-3509
Autor:
Agata Kieliszek, Daniel Mobilio, Blessing Bassey-Archibong, Jarrod Johnson, Chitra Venugopal, Jakob Magolan, Sheila Singh
Publikováno v:
Neuro-Oncology. 24:vii98-vii99
The current standard of care for (surgery and radiation) for brain metastases (BM) is inadequate as BM have a 90% mortality rate within one year of diagnosis, posing a large unmet clinical need. The Singh lab has generated a large in-house biobank of
Autor:
Minomi Subapanditha, Chitra Venugopal, Neil Winegarden, Ashley A. Adile, Robin M. Hallett, Blake Yarascavitch, John Provias, David Bakhshinyan, Blessing Bassey-Archibong, Neil Savage, Bradley W. Doble, Laura M. Richards, Dillon McKenna, Trevor J. Pugh, Olufemi Ajani, Owen Whitley, Nazanin Tatari, Michelle Kameda-Smith, Adam Fleming, Anna Dvorkin-Gheva, Branavan Manoranjan, Sheila K. Singh, Gary D. Bader
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Medulloblastoma (MB) is defined by four molecular subgroups (Wnt, Shh, Group 3, Group 4) with Wnt MB having the most favorable prognosis. Since prior reports have illustrated the antitumorigenic role of Wnt activation in Shh MB, we aimed to assess th
Publikováno v:
Neuro-oncology
Background Brain metastases (BM) are a frequent complication of malignant melanoma (MM), with limited treatment options and poor survival. Prevention of BM could be more effective and better tolerated than treating established BM in various condition
Autor:
Max A. K. Rätze, Thijs Koorman, Thijmen Sijnesael, Blessing Bassey-Archibong, Robert van de Ven, Lotte Enserink, Daan Visser, Sridevi Jaksani, Ignacio Viciano, Elvira R. M. Bakker, François Richard, Andrew Tutt, Lynda O’Leary, Amanda Fitzpatrick, Pere Roca-Cusachs, Paul J. van Diest, Christine Desmedt, Juliet M. Daniel, Clare M. Isacke, Patrick W. B. Derksen
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Invasive lobular breast carcinoma (ILC) is characterized by proliferative indolence and long-term latency relapses. This study aimed to identify how disseminating ILC cells control the balance between quiescence and cell cycle re-entry. In the absenc
Autor:
Agata Kieliszek, Daniel Mobilio, Blessing Bassey-Archibong, Jarrod Johnson, Dillon McKenna, Chitra Venugopal, Jakob Magolan, Sheila Singh
Publikováno v:
Neuro-Oncology Advances. 4:i3-i3
The current standard of care (surgery and radiation) for brain metastases (BM) is inadequate as BM have a 90% mortality rate within one year of diagnosis, posing a large unmet clinical need. The Singh lab has generated a large in-house biobank of pat
Autor:
Laura Kuhlmann, Shaikh Vm, Nazanin Tatari, Kevin R. Brown, Parvez Vora, Chitra Venugopal, Jason Moffat, Chirayu Chokshi, Dillon McKenna, Deepak Upreti, William D. Gwynne, Sheila K. Singh, Sabra K. Salim, Nadeem Murtaza, Neil Savage, Minomi Subapanditha, Piyasena D, Blessing Bassey-Archibong, Amanda Khoo, Mathieu Seyfrid, William T. Maich, David Bakhshinyan
PurposeGlioblastoma (GBM) patients suffer from a dismal prognosis, with standard of care therapy inevitably leading to therapy-resistant recurrent tumors. The presence of brain tumor initiating cells (BTICs) drives the extensive heterogeneity seen in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de99cdd2b806f297ecaa3fb8c8cbae57
https://doi.org/10.1101/2021.06.02.446670
https://doi.org/10.1101/2021.06.02.446670
Publikováno v:
Cancer Research. 82:976-976
BACKGROUND: The incidence of brain metastases (BM) is tenfold higher than that of primary brain tumors. BM predominantly originate from primary lung, breast, and melanoma tumors with a 90% mortality rate within one year of diagnosis, posing a large u