A high-throughput LC-MS/MS assay for piperaquine from dried blood spots: Improving malaria treatment in resource-limited settings.

Autor: Blessborn D; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Kaewkhao N; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Tarning J; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

Publikováno v: Journal of mass spectrometry and advances in the clinical lab [J Mass Spectrom Adv Clin Lab] 2023 Dec 30; Vol. 31, pp. 19-26. Date of Electronic Publication: 2023 Dec 30 (Print Publication: 2024).

High sensitivity methods to quantify chloroquine and its metabolite in human blood samples using LC-MS/MS

Autor: Kaewkhao, K, Chotivanich, K, Winterberg, M, Day, N, Tarning, J, Blessborn, D

Publikováno v: Bioanalysis

AIM: Chloroquine is an antimalarial drug used in the treatment of Plasmodium vivax malaria. Three methods to quantify chloroquine and its metabolite in blood matrices were developed and validated. METHODOLOGY AND RESULTS: Different high-throughput ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b9953a37f37971e1e23d2e9b9e1112a
http://ora.ox.ac.uk/objects/uuid:

Determinants of Primaquine and Carboxyprimaquine Exposures in Children and Adults with Plasmodium vivax Malaria.

Autor: Chu CS; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Watson JA; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Phyo AP; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Win HH; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Yotyingaphiram W; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Thinraow S; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Soe NL; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Aung AA; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Wilaisrisak P; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Kraft K; Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Imwong M; Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Hanpithakpong W; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Blessborn D; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Tarning J; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand., Proux S; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand., Ling C; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Nosten FH; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., White NJ; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Oct 18; Vol. 65 (11), pp. e0130221. Date of Electronic Publication: 2021 Aug 16.

High-throughput quantitation method for amodiaquine and desethylamodiaquine in plasma using supported liquid extraction technology.

Autor: Kaewkhao K; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. Electronic address: karnrawee@tropmedres.ac., Tarning J; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine & Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Blessborn D; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine & Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2021 Aug 01; Vol. 1179, pp. 122887. Date of Electronic Publication: 2021 Jul 31.

Impact of standard and long-lasting ivermectin formulations in cattle and buffalo on wild Anopheles survival on Sumba Island, Indonesia.

Autor: Kobylinski, Kevin C.¹ (AUTHOR) kobylinskikevin@yahoo.com, Satoto, Tri B. T.² (AUTHOR), Nurcahyo, Wisnu³ (AUTHOR), Nugraheni, Yudi Ratna³ (AUTHOR), Testamenti, Vincentius A.² (AUTHOR), Winata, I Putu B. A.⁴ (AUTHOR), Pono, Yosua L.⁴ (AUTHOR), Timoria, Diana⁵ (AUTHOR), Assawasuwannakit, Piyanan¹ (AUTHOR), Chambers, Mary^5,6 (AUTHOR), Baird, J. Kevin^6,7 (AUTHOR), Tarning, Joel^1,6 (AUTHOR), von Seidlein, Lorenz^1,6 (AUTHOR), Bøgh, Claus⁸ (AUTHOR)

Publikováno v: Scientific Reports. 11/30/2024, Vol. 14 Issue 1, p1-14. 14p.