Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Blerta Xhemalçe"'
Autor:
Wei-Ta Chen, Nancy D Ebelt, Travis H Stracker, Blerta Xhemalce, Carla L Van Den Berg, Kyle M Miller
Publikováno v:
eLife, Vol 4 (2015)
Ataxia-telangiectasia mutated (ATM) protein kinase regulates the DNA damage response (DDR) and is associated with cancer suppression. Here we report a cancer-promoting role for ATM. ATM depletion in metastatic cancer cells reduced cell migration and
Externí odkaz:
https://doaj.org/article/b022db6c1de84b82ba2b3a3238f5860f
Autor:
Samantha B. Shelton, Nakul M. Shah, Nathan S. Abell, Sravan K. Devanathan, Marvin Mercado, Blerta Xhemalçe
Publikováno v:
Cell Reports, Vol 22, Iss 6, Pp 1374-1383 (2018)
Summary: RNAP II switching from the paused to the productive transcription elongation state is a pivotal regulatory step that requires specific phosphorylations catalyzed by the P-TEFb kinase. Nucleosolic P-TEFb activity is inhibited by its interacti
Externí odkaz:
https://doaj.org/article/bd2a55bdc6824da2a0698ba7630c590d
Autor:
Calder W Reinsborough, Hélène Ipas, Nathan S Abell, Ryan M Nottingham, Jun Yao, Sravan K Devanathan, Samantha B Shelton, Alan M Lambowitz, Blerta Xhemalçe
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008273 (2019)
5' ends are important for determining the fate of RNA molecules. BCDIN3D is an RNA phospho-methyltransferase that methylates the 5' monophosphate of specific RNAs. In order to gain new insights into the molecular function of BCDIN3D, we performed an
Externí odkaz:
https://doaj.org/article/69e758f60ce54878b625e4b241cbc63e
Autor:
Blerta Xhemalçe
Publikováno v:
The FASEB Journal. 36
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006139 (2016)
RNA levels are widely thought to be predictive of RNA function. However, the existence of more than a hundred chemically distinct modifications of RNA alone is a major indication that these moieties may impart distinct functions to subgroups of RNA m
Externí odkaz:
https://doaj.org/article/a0337f9db4164fc294a8cbab0627b676
Autor:
Mark A. Dawson, Samuel D. Foster, Andrew J. Bannister, Samuel C. Robson, Rebecca Hannah, Xiaonan Wang, Blerta Xhemalce, Andrew D. Wood, Anthony R. Green, Berthold Göttgens, Tony Kouzarides
Publikováno v:
Cell Reports, Vol 2, Iss 3, Pp 470-477 (2012)
The JAK2 tyrosine kinase is a critical mediator of cytokine-induced signaling. It plays a role in the nucleus, where it regulates transcription by phosphorylating histone H3 at tyrosine 41 (H3Y41ph). We used chromatin immunoprecipitation coupled to m
Externí odkaz:
https://doaj.org/article/ab41808cb7824feba4f92a5c2bea78b2