Výsledky vyhledávání - "Blenda C.K. Wong"

Non-invasive prenatal detection of fetal trisomy 18 by RNA-SNP allelic ratio analysis using maternal plasma SERPINB2 mRNA: a feasibility study

Autor: Rossa W.K. Chiu, Tze K. Lau, Blenda C.K. Wong, Y.M. Dennis Lo, Nancy B.Y. Tsui, Tak Yeung Leung

Publikováno v: Prenatal Diagnosis. 29:1031-1037

Objective Non-invasive prenatal diagnosis of chromosome aneuploidies has been achieved by measuring the ratio of two alleles of a single nucleotide polymorphism (SNP) in circulating placental mRNA (the RNA–SNP allelic ratio approach) in maternal pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74053f72016731fa16529e0ac4692bb1
https://doi.org/10.1002/pd.2340

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Reduced Plasma RNA Integrity in Nasopharyngeal Carcinoma Patients

Autor: Katherine C.K. Chow, Y.M. Dennis Lo, Anthony T.C. Chan, Lisa Y.S. Chan, Sing Fai Leung, Blenda C.K. Wong, K.C. Allen Chan

Publikováno v: Clinical Cancer Research. 12:2512-2516

Purpose: Recent research has shown the feasibility of detecting cell-free RNA markers in human subjects. As elevated RNase activity has previously been described in the circulation of cancer patients, we hypothesized that cancer patients may have red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc35ee492f48c068c3cbcf02f59f5c2
https://doi.org/10.1158/1078-0432.ccr-05-2572

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Plasma RNA integrity analysis: methodology and validation

Autor: Blenda C.K. Wong, Y.M. Dennis Lo

Publikováno v: Annals of the New York Academy of Sciences. 1075

The detection of cell-free RNA in plasma and serum of human subjects has found increasing applications in the field of medical diagnostics. However, many questions regarding the biology of circulating RNA remain to be addressed. One issue concerns th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f0655ccb7b189fce9017d30ba4cbd1
https://pubmed.ncbi.nlm.nih.gov/17108208

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Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: implications for noninvasive prenatal diagnosis and monitoring

Autor: K.C. Allen Chan, Rossa W.K. Chiu, Blenda C.K. Wong, Tse N. Leung, Lin W. Chan, Nancy B.Y. Tsui, Y.M. Dennis Lo, Tze K. Lau

Publikováno v: Clinical chemistry. 51(10)

Background: The molecular characteristics of placental RNA circulating in maternal plasma are unknown. We investigated the integrity of circulating placental RNA in maternal plasma and tested the relevance of plasma RNA integrity for noninvasive pren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a30b80dd209feb4b822546772acc839
https://pubmed.ncbi.nlm.nih.gov/16081506

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Cell-free DNA and RNA in plasma as new tools for molecular diagnostics

Autor: Blenda C.K. Wong, Y.M. Dennis Lo

Publikováno v: Expert review of molecular diagnostics. 3(6)

The recent interest in plasma nucleic acids has opened up many new promising possibilities for the noninvasive detection and monitoring of a variety of diseases. The discovery of tumor-derived DNA in the plasma of cancer patients has provided an alte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cac3ffc753a4e2b24c9208905117fe
https://pubmed.ncbi.nlm.nih.gov/14628906

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Correction

Autor: Lin Wai Chan, Tse Ngong Leung, Blenda C.K. Wong, Yuk Ming Dennis Lo, Rossa W.K. Chiu, Tze K. Lau, Kwan Chee Chan, Nancy B.Y. Tsui

Publikováno v: Clinical Chemistry. 52:909-909

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dc3fe944bcce48fc9c3b5083bca1425
https://doi.org/10.1373/clinchem.2006.068429

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