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of 48
pro vyhledávání: '"Bleck Cke"'
Mitochondrial networks provide coordinated energy distribution throughout muscle cells. However, pathways specifying mitochondrial network-type separately from contractile fiber-type remain unclear. Here, we show that natural energetic demands placed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da2adf9c38d4128dcbdc90fac1673aa7
https://doi.org/10.1101/2021.09.30.462204
https://doi.org/10.1101/2021.09.30.462204
Skeletal muscles play a central role in human movement through forces transmitted by contraction of the sarcomere. We recently showed that mammalian sarcomeres are connected through frequent branches forming a singular, mesh-like myofibrillar matrix.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b0b27a69318ca7c51b2262660f4ad39
https://doi.org/10.1101/2021.10.01.462603
https://doi.org/10.1101/2021.10.01.462603
Cellular development requires the integrated assembly of intracellular structures into functionally specialized regions supporting overall cellular performance. However, it remains unclear how coordination of organelle interactions contributes to dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c2d2aee59580428651738234195d2f
https://doi.org/10.1101/2021.06.16.448433
https://doi.org/10.1101/2021.06.16.448433
Autor:
Sara Saez-Atienzar, Ravindran Kumaran, Yi Li, Bleck Cke, Chad D. Williamson, Adamantios Mamais, Natalie Landeck, A Beilina, Jillian H. Kluss, Luis Bonet-Ponce, Eric Lindberg, Mark R. Cookson
Mutations in the leucine rich repeat kinase 2 (LRRK2) gene are a cause of familial and sporadic Parkinson’s disease (PD). Nonetheless, the biological functions of LRRK2 remain incompletely understood. Here, we observed that LRRK2 is recruited to ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09a2476490934eed8855bce4efcdee7
Autor:
Beck, Tatyana Tenkova-Heuser, Bleck Cke, Matthias Garten, John E. Heuser, Robyn Roth, Joshua Zimmerberg, Daniel E. Goldberg
While membrane contact sites (MCS) between intracellular organelles are abundant1, and cell-cell junctions are classically defined2, very little is known about the contacts between membranes that delimit extracellular junctions within cells, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b85537d25aea97ddf51315ce1e1a9d
Autor:
Jinhui Ding, Sara Saez-Atienzar, Yingfang Li, Bleck Cke, Sampieri L, Nathan A. Smith, du Hoffmann J, Mark R. Cookson, Dorien A. Roosen, Natalie Landeck, Patrick A. Lewis, Jillian H. Kluss, Chad D. Williamson, A Beilina, Luis Bonet-Ponce, Juan S. Bonifacino, Ravindran Kumaran, David C. Gershlick, Chen-Yu Liu, Alice Kaganovich, Melissa M. Conti
Parkinson’s disease (PD) is a common neurodegenerative motor disorder characterized in part by neuropathological lesions in the nigrostriatal pathway. While most cases of PD are sporadic in nature, several inherited monogenic syndromes exist that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508b661093b2754e8795785dd7bcb8f3
Autor:
Zhe Chen, Dillon J. Chung, Christian A. Combs, Robert S. Balaban, Zong-Heng Wang, Bleck Cke, Huichun Xu, Eric Lindberg, Grey P. Madison, Guofeng Zhang
Although mitochondrial DNA (mtDNA) is prone to mutation and not all conventional DNA repair systems operate in mitochondria, deleterious mutations are exceedingly rare. How the transmission of detrimental mtDNA mutations is restricted through the mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f757d0dcf8a0649ac062fec4ad061
https://doi.org/10.1101/646638
https://doi.org/10.1101/646638
Publikováno v:
EMBO JOURNAL
Vaccinia virus (VACV) the model poxvirus produces two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and therefore require an unusual cellular entry mechanism. By a combination
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Autor:
Kim Y; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; Department of Physical Therapy and Kinesiology, University of Massachusetts Lowell, Massachusetts, USA., Parry HA; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Willingham TB; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Alspaugh G; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Lindberg E; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Combs CA; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Knutson JR; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Bleck CKE; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Glancy B; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.; National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Publikováno v:
The Journal of physiology [J Physiol] 2024 Mar; Vol. 602 (5), pp. 891-912. Date of Electronic Publication: 2024 Mar 01.