Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.

Autor: McElyea SD; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Starbuck JM; Department of Orthodontics and Facial Genetics, Indiana University School of Dentistry, 1121 W. Michigan Street, DS 250B, Indianapolis, IN 46202, USA.; Department of Anthropology, University of Central Florida, 4000 Central Florida Blvd., Howard Phillips Hall, Room 309F, Orlando, FL 32816, USA, Tumbleson-Brink DM; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Harrington E; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Blazek JD; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Ghoneima A; Department of Orthodontics and Facial Genetics, Indiana University School of Dentistry, 1121 W. Michigan Street, DS 250B, Indianapolis, IN 46202, USA., Kula K; Department of Orthodontics and Facial Genetics, Indiana University School of Dentistry, 1121 W. Michigan Street, DS 250B, Indianapolis, IN 46202, USA., Roper RJ; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2016 Nov 15; Vol. 25 (22), pp. 4856-4869.

Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.

Autor: Blazek JD; Department of Biology, Indiana University-Purdue University Indianapolis and Indiana University Center for Regenerative Biology and Medicine, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Malik AM; Department of Biology, Indiana University-Purdue University Indianapolis and Indiana University Center for Regenerative Biology and Medicine, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Tischbein M; Department of Biology, Franklin and Marshall College, PO Box 3003, Lancaster, PA 17604, USA., Arbones ML; Department of Developmental Biology, Institut de Biologia Molecular de Barcelona IBMB- CSIC, and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Barcelona 08028, Spain., Moore CS; Department of Biology, Franklin and Marshall College, PO Box 3003, Lancaster, PA 17604, USA., Roper RJ; Department of Biology, Indiana University-Purdue University Indianapolis and Indiana University Center for Regenerative Biology and Medicine, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA. Electronic address: rjroper@iupui.edu.

Publikováno v: Mechanisms of development [Mech Dev] 2015 May; Vol. 136, pp. 133-42. Date of Electronic Publication: 2014 Dec 30.

Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.

Autor: Blazek JD; Department of Biology, Indiana University-Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN 46202, USA., Gaddy A, Meyer R, Roper RJ, Li J

Publikováno v: Bone [Bone] 2011 Feb; Vol. 48 (2), pp. 275-80. Date of Electronic Publication: 2010 Sep 24.