Výsledky vyhledávání - "Blazej M. Skrobek"

Akademický článek

Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins

Autor: Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances J. D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, Blazej M. Skrobek, Katarzyna Radziwon, John Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

Single particle cryo-electron microscopy of membrane proteins is limited by their small size and difficulty to orient. Here the authors generate recombinant antibodies against the 12 kDa fusion partner BRIL domain from apocytochrome b562 to use them

Externí odkaz: https://doaj.org/article/c4e601bd5c28456ba07689558d4667e5

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Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA

Autor: Satchal K. Erramilli, Pawel K. Dominik, Dawid Deneka, Piotr Tokarz, Sangwoo S. Kim, Bharat G. Reddy, Blazej M. Skrobek, Olivier Dalmas, Eduardo Perozo, Anthony A. Kossiakoff

Publikováno v: bioRxiv

CorA, the primary magnesium ion channel in prokaryotes and archaea, is a prototypical homopentameric ion channel that undergoes ion-dependent conformational transitions. CorA adopts five-fold symmetric non-conductive states in the presence of high co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d9aab3e6e66892dd26d639718c88d2
https://doi.org/10.1101/2023.05.07.539746

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