Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Blaza, JN"'
Autor:
Fitzpatrick, AWP, Llabrés, S, Neuberger, A, Blaza, JN, Bai, X-C, Okada, U, Murakami, S, Van Veen, HW, Zachariae, U, Scheres, SHW, Luisi, BF, Du, D
The MacA-MacB-TolC assembly of Escherichia coli is a transmembrane machine that spans the cell envelope and actively extrudes substrates, including macrolide antibiotics and polypeptide virulence factors. These transport processes are energized by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7bf00ff2c3d71c5bee665b9a7f56ce
https://www.repository.cam.ac.uk/handle/1810/266255
https://www.repository.cam.ac.uk/handle/1810/266255
Bacterial efflux pumps confer multidrug resistance by transporting diverse antibiotics from the cell. In Gram-negative bacteria, some of these pumps form multi-protein assemblies that span the cell envelope. Here, we report the near-atomic resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945ccf4d4520aa93cb8e239d851da0f6
Autor:
Barrett J; Department of Biology, University of York, York, UK.; Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK., Naduthodi MIS; Department of Biology, University of York, York, UK.; Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK., Mao Y; Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Engineering Biology, University of Edinburgh, Edinburgh, UK., Dégut C; Department of Biology, University of York, York, UK., Musiał S; Department of Biology, University of York, York, UK.; Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK., Salter A; Department of Biology, University of York, York, UK.; Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK., Leake MC; Department of Biology, University of York, York, UK.; School of Physics, Engineering and Technology, University of York, York, UK., Plevin MJ; Department of Biology, University of York, York, UK.; York Structural Biology Laboratory, University of York, York, UK., McCormick AJ; Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Engineering Biology, University of Edinburgh, Edinburgh, UK., Blaza JN; York Structural Biology Laboratory, University of York, York, UK.; Department of Chemistry, University of York, York, UK., Mackinder LCM; Department of Biology, University of York, York, UK. luke.mackinder@york.ac.uk.; Centre for Novel Agricultural Products (CNAP), Department of Biology, University of York, York, UK. luke.mackinder@york.ac.uk.
Publikováno v:
Nature plants [Nat Plants] 2024 Nov; Vol. 10 (11), pp. 1801-1813. Date of Electronic Publication: 2024 Oct 09.
Autor:
Nam O; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK., Musiał S; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK., Demulder M; Biozentrum, University of Basel, Spitalstrasse 41, 4056 Basel, Switzerland., McKenzie C; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK., Dowle A; Department of Biology, University of York, York YO10 5DD, UK., Dowson M; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK., Barrett J; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK., Blaza JN; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, UK., Engel BD; Biozentrum, University of Basel, Spitalstrasse 41, 4056 Basel, Switzerland. Electronic address: ben.engel@unibas.ch., Mackinder LCM; Department of Biology, University of York, York YO10 5DD, UK; Centre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK. Electronic address: luke.mackinder@york.ac.uk.
Publikováno v:
Cell [Cell] 2024 Oct 17; Vol. 187 (21), pp. 5935-5950.e18. Date of Electronic Publication: 2024 Oct 04.
Autor:
Rowland RJ; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK., Korolchuk S; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.; Fujifilm, Belasis Ave, Stockton-on-Tees, Billingham, TS23 1LH, UK., Salamina M; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.; Evotec (UK) Ltd., Milton, Abingdon, OX14 4RZ, UK., Tatum NJ; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK., Ault JR; Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK., Hart S; York Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK., Turkenburg JP; York Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK., Blaza JN; York Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK., Noble MEM; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. martin.noble@ncl.ac.uk., Endicott JA; Translational and Clinical Research Institute, Newcastle University Centre for Cancer, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. jane.endicott@ncl.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2024 Aug 09; Vol. 15 (1), pp. 6807. Date of Electronic Publication: 2024 Aug 09.
Autor:
Bardy P; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG., MacDonald CIW; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom., Kirchberger PC; Department of Microbiology & Molecular Genetics, Oklahoma State University, US., Jenkins HT; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG., Botka T; Department of Experimental Biology, Faculty of Science, Masaryk University, 625 00, Brno, Czech Republic., Byrom L; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG.; Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Alim NTB; Department of Microbiology and Immunology, University of British Columbia, Vancouver, V6T 1Z3, BC, Canada., Traore DAK; Materials and Structural Analysis, Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG, Eindhoven, The Netherlands., König HC; Department of Microbiology and Immunology, University of British Columbia, Vancouver, V6T 1Z3, BC, Canada., Nicholas TR; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG., Chechik M; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG., Hart SJ; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom., Turkenburg JP; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom., Blaza JN; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG., Beatty JT; Department of Microbiology and Immunology, University of British Columbia, Vancouver, V6T 1Z3, BC, Canada., Fogg PCM; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG.; Department of Biology, University of York, Wentworth Way, York, YO10 5DD, UK., Antson AA; York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, United Kingdom.; York Biomedical Research Institute, University of York, York, United Kingdom. YO10 5NG.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 11. Date of Electronic Publication: 2024 Jun 11.
Autor:
Mahmood M; Cancer Research UK Scotland Institute, Glasgow, UK., Liu EM; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shergold AL; Cancer Research UK Scotland Institute, Glasgow, UK., Tolla E; Cancer Research UK Scotland Institute, Glasgow, UK., Tait-Mulder J; Cancer Research UK Scotland Institute, Glasgow, UK., Huerta-Uribe A; Cancer Research UK Scotland Institute, Glasgow, UK., Shokry E; Cancer Research UK Scotland Institute, Glasgow, UK., Young AL; Cancer Research UK Scotland Institute, Glasgow, UK., Lilla S; Cancer Research UK Scotland Institute, Glasgow, UK., Kim M; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Park T; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Boscenco S; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Manchon JL; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain., Rodríguez-Antona C; Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras CIBERER, Madrid, Spain., Walters RC; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Springett RJ; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Blaza JN; Structural Biology Laboratory and York Biomedical Research Institute, Department of Chemistry, The University of York, York, UK., Mitchell L; Cancer Research UK Scotland Institute, Glasgow, UK., Blyth K; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Zanivan S; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Sumpton D; Cancer Research UK Scotland Institute, Glasgow, UK., Roberts EW; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Reznik E; Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org.; Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. reznike@mskcc.org., Gammage PA; Cancer Research UK Scotland Institute, Glasgow, UK. payam.gammage@glasgow.ac.uk.; School of Cancer Sciences, University of Glasgow, Glasgow, UK. payam.gammage@glasgow.ac.uk.
Publikováno v:
Nature cancer [Nat Cancer] 2024 Apr; Vol. 5 (4), pp. 659-672. Date of Electronic Publication: 2024 Jan 29.
Autor:
Helena-Bueno K; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Rybak MY; Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX, USA., Ekemezie CL; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Sullivan R; School of Biosciences, University of Birmingham, Birmingham, UK., Brown CR; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Dingwall C; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Baslé A; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Schneider C; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Connolly JPR; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK., Blaza JN; Department of Chemistry, University of York, York, UK.; York Structural Biology Laboratory, University of York, York, UK.; York Biomedical Research Institute, University of York, York, UK., Csörgő B; Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, Szeged, Hungary., Moynihan PJ; School of Biosciences, University of Birmingham, Birmingham, UK., Gagnon MG; Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX, USA. magagnon@utmb.edu.; Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA. magagnon@utmb.edu.; Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, USA. magagnon@utmb.edu.; Institute for Human Infections & Immunity, University of Texas Medical Branch, Galveston, TX, USA. magagnon@utmb.edu., Hill CH; York Structural Biology Laboratory, University of York, York, UK. chris.hill@york.ac.uk.; York Biomedical Research Institute, University of York, York, UK. chris.hill@york.ac.uk.; Department of Biology, University of York, York, UK. chris.hill@york.ac.uk., Melnikov SV; Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK. sergey.melnikov@newcastle.ac.uk.
Publikováno v:
Nature [Nature] 2024 Feb; Vol. 626 (8001), pp. 1125-1132. Date of Electronic Publication: 2024 Feb 14.
Autor:
Li J; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Sharma M; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Meek R; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Alhifthi A; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au.; Chemistry Department, Faculty of Science (Female Section), Jazan University Jazan 82621 Saudi Arabia., Armstrong Z; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Soler NM; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research Parkville Victoria 3010 Australia., Lee M; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Goddard-Borger ED; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research Parkville Victoria 3010 Australia.; Department of Medical Biology, University of Melbourne Parkville Victoria 3010 Australia., Blaza JN; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Davies GJ; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Williams SJ; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au.
Publikováno v:
Chemical science [Chem Sci] 2023 Dec 12; Vol. 15 (2), pp. 778-779. Date of Electronic Publication: 2023 Dec 12 (Print Publication: 2024).
Autor:
Li J; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Sharma M; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Meek R; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Alhifthi A; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au.; Chemistry Department, Faculty of Science (Female Section), Jazan University Jazan 82621 Saudi Arabia., Armstrong Z; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Soler NM; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research Parkville Victoria 3010 Australia., Lee M; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au., Goddard-Borger ED; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research Parkville Victoria 3010 Australia.; Department of Medical Biology, University of Melbourne Parkville Victoria 3010 Australia., Blaza JN; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Davies GJ; York Structural Biology Laboratory, Department of Chemistry, University of York York YO10 5DD UK gideon.davies@york.ac.uk., Williams SJ; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne Parkville Victoria 3010 Australia sjwill@unimelb.edu.au.
Publikováno v:
Chemical science [Chem Sci] 2023 Sep 25; Vol. 14 (41), pp. 11429-11440. Date of Electronic Publication: 2023 Sep 25 (Print Publication: 2023).