Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Blasco Morozzo Della Rocca"'
Autor:
Gonçalo Paulo, Ke Sun, Giovanni Di Muccio, Alberto Gubbiotti, Blasco Morozzo della Rocca, Jia Geng, Giovanni Maglia, Mauro Chinappi, Alberto Giacomello
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Signal transmission in the brain relies on voltage-gated ion channels, which exhibit the electrical behaviour of memristors, resistors with memory. State-of-the-art technologies currently employ semiconductor-based neuromorphic approaches, w
Externí odkaz:
https://doaj.org/article/2fba14ff007c46dca0f38667d83ed91c
Autor:
Fanny Bétermier, Benjamin Cressiot, Giovanni Di Muccio, Nathalie Jarroux, Laurent Bacri, Blasco Morozzo della Rocca, Mauro Chinappi, Juan Pelta, Jean-Marie Tarascon
Publikováno v:
Communications Materials, Vol 1, Iss 1, Pp 1-11 (2020)
The design of advanced batteries relies on careful control of molecular interactions. Here, a protein nanopore, inserted into a lipid membrane, is shown to discern supramolecular polysulfide/cyclodextrin complexes differing by a single sulfur atom, a
Externí odkaz:
https://doaj.org/article/52397670edb04de2b293d21eb0829b92
Autor:
Alessio Ottaviani, Federico Iacovelli, Joshua Welsch, Blasco Morozzo della Rocca, Alessandro Desideri, Mattia Falconi, Laurent Calcul, Bill J. Baker, Paola Fiorani
Publikováno v:
Cells, Vol 11, Iss 21, p 3486 (2022)
Human topoisomerase 1B regulates the topological state of supercoiled DNA enabling all fundamental cell processes. This enzyme, which is the unique molecular target of the natural anticancer compound camptothecin, acts by nicking one DNA strand and f
Externí odkaz:
https://doaj.org/article/d69ee54c831e4dc4be5dabbb01e767cf
Autor:
Veronica Di Paolo, Chiara Fulci, Dante Rotili, Francesca Sciarretta, Alessia Lucidi, Blasco Morozzo della Rocca, Anastasia De Luca, Antonio Rosato, Luigi Quintieri, Anna Maria Caccuri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1131-1139 (2019)
The antitumor agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (1) is a potent inhibitor of GSTP1-1, a glutathione S-transferase capable of inhibiting apoptosis by binding to JNK1 and TRAF2. We recently demonstrated that, unlike its par
Externí odkaz:
https://doaj.org/article/7658832476ab4c16a9cb9de4edf953e6
Autor:
Chiara Fulci, Dante Rotili, Anastasia De Luca, Lorenzo Stella, Blasco Morozzo della Rocca, Mariantonietta Forgione, Veronica Di Paolo, Antonello Mai, Mattia Falconi, Luigi Quintieri, Anna M. Caccuri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 240-247 (2017)
Context: The nitrobezoxadiazole derivative NBDHEX is a potent inhibitor of glutathione transferase P1-1 (GSTP1-1) endowed with outstanding anticancer activity in different tumor models. Objective: To characterize by in vitro biochemical and in silico
Externí odkaz:
https://doaj.org/article/3789f8d2549b4ac8b31477f4b3596ba3
Publikováno v:
Nature nanotechnology.
Autor:
Alice Romagnoli, Mattia D’Agostino, Eleonora Pavoni, Chiara Ardiccioni, Stefano Motta, Paolo Crippa, Giorgio Biagetti, Valentina Notarstefano, Jesmina Rexha, Nunzio Perta, Simone Barocci, Brianna K. Costabile, Gabriele Colasurdo, Sara Caucci, Davide Mencarelli, Claudio Turchetti, Marco Farina, Luca Pierantoni, Anna La Teana, Richard Al Hadi, Francesco Cicconardi, Mauro Chinappi, Emiliano Trucchi, Filippo Mancia, Stefano Menzo, Blasco Morozzo della Rocca, Ilda D’Annessa, Daniele Di Marino
Publikováno v:
Nano today. 48
Reliable point-of-care (POC) rapid tests are crucial to detect infection and contain the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The emergence of several variants of concern (VOC) can reduce binding affinity to diagnos
Autor:
Alice Romagnoli, Luca Pierantoni, Blasco Morozzo della Rocca, Emiliano Trucchi, Filippo Mancia, Paolo Crippa, Claudio Turchetti, Chiara Ardiccioni, Eleonora Pavoni, Sara Caucci, Anna La Teana, Simone Barocci, Ilda D'Annessa, Mauro Chinappi, Valentina Notarstefano, Gabriele Colasurdo, Marco Farina, Richard Al Hadi, Brianna K. Costabile, Stefano Motta, Daniele Di Marino, Giorgio Biagetti, Davide Mencarelli, Mattia D'Agostino
Fast, reliable and point-of-care systems to detect the SARS-CoV-2 infection are crucial to contain viral spreading and to adopt timely clinical treatments. Many of the rapid detection tests currently in use are based on antibodies that bind viral pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb258675362e4c3b84132907ef9a504f
https://doi.org/10.1101/2021.10.02.21264210
https://doi.org/10.1101/2021.10.02.21264210
Selectivity towards positive and negative ions in nanopores is often associated with electroosmotic flow, the control of which is pivotal in several micro-nanofluidic technologies. Selectivity is traditionally understood to be a consequence of surfac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bd1795019a3cedb4a1327fc49aaf5a