Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Blanka Stiburkova"'
Autor:
Aleš Kvasnička, David Friedecký, Radana Brumarová, Markéta Pavlíková, Kateřina Pavelcová, Jana Mašínová, Lenka Hasíková, Jakub Závada, Karel Pavelka, Pavel Ješina, Blanka Stibůrková
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Currently, it is not possible to predict whether patients with hyperuricemia (HUA) will develop gout and how this progression may be affected by urate-lowering treatment (ULT). Our study aimed to evaluate differences in plasma lip
Externí odkaz:
https://doaj.org/article/31ac9cfa6c504c3cbf5bfdb4c1ca733a
Autor:
Lucie Andres Cerezo, Adéla Navrátilová, Hana Hulejová, Markéta Pavlíková, Jakub Závada, Karel Pavelka, Ladislav Šenolt, Blanka Stiburkova
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-7 (2023)
Abstract Objectives IL-37 is an anti-inflammatory cytokine involved in inflammatory and autoimmune diseases. We aimed to investigate the association between IL-37 genetic variants, IL-37 plasma levels, and various clinical phases of gout. Methods The
Externí odkaz:
https://doaj.org/article/0b397d3ce9954805b5cac16c05b19922
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background ABCG2 is a high-capacity urate transporter that plays a crucial role in renal urate overload and extra-renal urate underexcretion. Previous studies have suggested an association between hyperuricemia and gout susceptibility relati
Externí odkaz:
https://doaj.org/article/eabeafd0922d4141b2c23c10f17ccffb
Autor:
Daisuke Miyamoto, Nana Sato, Koji Nagata, Yukinao Sakai, Hitoshi Sugihara, Yuki Ohashi, Blanka Stiburkova, Ivan Sebesta, Kimiyoshi Ichida, Ken Okamoto
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1584 (2022)
Renal hypouricemia is a disease caused by the dysfunction of renal urate transporters. This disease is known to cause exercise-induced acute kidney injury, but its mechanism has not yet been established. To analyze the mechanism by which hypouricemia
Externí odkaz:
https://doaj.org/article/c04a5bb915034e14b106332916683b4c
Publikováno v:
BMC Pediatrics, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background Renal hypouricemia is a rare heterogeneous inherited disorder characterized by impaired tubular uric acid transport, reabsorption insufficiency and /or acceleration of secretion. The affected individuals are predisposed to nephrol
Externí odkaz:
https://doaj.org/article/24b8234fee0144bea972d81b941f83ce
Autor:
Yu Toyoda, Kateřina Pavelcová, Martin Klein, Hiroshi Suzuki, Tappei Takada, Blanka Stiburkova
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-3 (2019)
Externí odkaz:
https://doaj.org/article/c6c236d2fe534e96896b42f6f2857ce3
Autor:
Blanka Stiburkova, Jana Bohatá, Kateřina Pavelcová, Velibor Tasic, Dijana Plaseska-Karanfilska, Sung-Kweon Cho, Ludmila Potočnaková, Jana Šaligová
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1607 (2021)
Renal hypouricemia (RHUC) is caused by an inherited defect in the main reabsorption system of uric acid, SLC22A12 (URAT1) and SLC2A9 (GLUT9). RHUC is characterized by a decreased serum uric acid concentration and an increase in its excreted fraction.
Externí odkaz:
https://doaj.org/article/f04b0b6447f749a39a7891cde2aa2bed
Autor:
Eresha Jasinge, Grace Angeline Malarnangai Kularatnam, Hewa Warawitage Dilanthi, Dinesha Maduri Vidanapathirana, Kandana Liyanage Subhashinie Priyadarshika Kapilani Menike Jayasena, Nambage Dona Priyani Dhammika Chandrasiri, Neluwa Liyanage Ruwan Indika, Pyara Dilani Ratnayake, Vindya Nandani Gunasekara, Lynette Dianne Fairbanks, Blanka Stiburkova
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Abstract Background Uric acid is the metabolic end product of purine metabolism in humans. Altered serum and urine uric acid level (both above and below the reference ranges) is an indispensable marker in detecting rare inborn errors of metabolism. W
Externí odkaz:
https://doaj.org/article/a02bb55bacc249e286795603e7459355
Autor:
Yu Toyoda, Kateřina Pavelcová, Jana Bohatá, Pavel Ješina, Yu Kubota, Hiroshi Suzuki, Tappei Takada, Blanka Stiburkova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1935 (2021)
The ABCG2 gene is a well-established hyperuricemia/gout risk locus encoding a urate transporter that plays a crucial role in renal and intestinal urate excretion. Hitherto, p.Q141K—a common variant of ABCG2 exhibiting approximately one half the cel
Externí odkaz:
https://doaj.org/article/395471d0d21c4d02a50d5ee2862912f8
Autor:
Blanka Stiburkova, Jana Bohata, Iveta Minarikova, Andrea Mancikova, Jiri Vavra, Vladimír Krylov, Zdenek Doležel
Publikováno v:
Applied Sciences, Vol 9, Iss 17, p 3479 (2019)
Renal hypouricemia (RHUC) is caused by an inherited defect in the main (reabsorptive) renal urate transporters, URAT1 and GLUT9. RHUC is characterized by decreased concentrations of serum uric acid and an increase in its excretion fraction. Patients
Externí odkaz:
https://doaj.org/article/c8fad83cc0eb48d29887ebc9e090eeaf