Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Blanka Stibůrková"'
Autor:
Aleš Kvasnička, David Friedecký, Radana Brumarová, Markéta Pavlíková, Kateřina Pavelcová, Jana Mašínová, Lenka Hasíková, Jakub Závada, Karel Pavelka, Pavel Ješina, Blanka Stibůrková
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Currently, it is not possible to predict whether patients with hyperuricemia (HUA) will develop gout and how this progression may be affected by urate-lowering treatment (ULT). Our study aimed to evaluate differences in plasma lip
Externí odkaz:
https://doaj.org/article/31ac9cfa6c504c3cbf5bfdb4c1ca733a
Autor:
Yu Toyoda, Sung Kweon Cho, Velibor Tasic, Kateřina Pavelcová, Jana Bohatá, Hiroshi Suzuki, Victor A. David, Jaeho Yoon, Anna Pallaiova, Jana Šaligová, Darryl Nousome, Raul Cachau, Cheryl A. Winkler, Tappei Takada, Blanka Stibůrková
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Renal hypouricemia (RHUC) is a pathological condition characterized by extremely low serum urate and overexcretion of urate in the kidney; this inheritable disorder is classified into type 1 and type 2 based on causative genes encoding physiologicall
Externí odkaz:
https://doaj.org/article/ecdfaf66f7f345c7b069c74d26b40df9
Autor:
Viktor Kožich, Bernd C Schwahn, Jitka Sokolová, Michaela Křížková, Tamas Ditroi, Jakub Krijt, Youssef Khalil, Tomáš Křížek, Tereza Vaculíková-Fantlová, Blanka Stibůrková, Philippa Mills, Peter Clayton, Kristýna Barvíková, Holger Blessing, Jolanta Sykut-Cegielska, Carlo Dionisi-Vici, Serena Gasperini, Ángeles García-Cazorla, Tobias B Haack, Tomáš Honzík, Pavel Ješina, Alice Kuster, Lucia Laugwitz, Diego Martinelli, Francesco Porta, René Santer, Guenter Schwarz, Peter Nagy
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102517- (2022)
Regulation of H2S homeostasis in humans is poorly understood. Therefore, we assessed the importance of individual enzymes in synthesis and catabolism of H2S by studying patients with respective genetic defects. We analyzed sulfur compounds (including
Externí odkaz:
https://doaj.org/article/c104284c656d4baba6f0fc3dc95350b4
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Abstract Objectives MicroRNAs (miRNAs) are short single-stranded RNAs that play a role in the post-transcriptional regulation of gene expression. Their deregulation can be associated with various diseases, such as cancer, neurodegenerative, and immun
Externí odkaz:
https://doaj.org/article/e42aaecfac7b4f1d9315de02b2b40a16
Autor:
Jiří Vávra, Andrea Mančíková, Kateřina Pavelcová, Lenka Hasíková, Jana Bohatá, Blanka Stibůrková
Publikováno v:
Cells, Vol 11, Iss 7, p 1063 (2022)
The OAT1 (SLC22A6) and OAT3 (SLC22A8) urate transporters are located on the basolateral membrane of the proximal renal tubules, where they ensure the uptake of uric acid from the urine back into the body. In a cohort of 150 Czech patients with primar
Externí odkaz:
https://doaj.org/article/51fca690f87947968790cbab6e029aaa
Autor:
Olha Hurba, Andrea Mancikova, Vladimir Krylov, Marketa Pavlikova, Karel Pavelka, Blanka Stibůrková
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107902 (2014)
ObjectiveUsing European descent Czech populations, we performed a study of SLC2A9 and SLC22A12 genes previously identified as being associated with serum uric acid concentrations and gout. This is the first study of the impact of non-synonymous allel
Externí odkaz:
https://doaj.org/article/9ac78a62ca254f5b8de05762a4e17dbe
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97646 (2014)
Uric acid is the end product of purine metabolism in humans, and increased serum uric acid concentrations lead to gout. The objective of the current study was to identify factors that are independently associated with serum uric acid concentrations i
Externí odkaz:
https://doaj.org/article/0ec39de737654739bbcf52da2096423d
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
ObjectivesMicroRNAs (miRNAs) are short single-stranded RNAs that play a role in the post-transcriptional regulation of gene expression. Their deregulation can be associated with various diseases, such as cancer, neurodegenerative, and immune-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92893e76b4b311ca3ba05f5fed6df9d9
https://doi.org/10.1186/s13075-021-02569-w
https://doi.org/10.1186/s13075-021-02569-w
Autor:
Marie Zikanova, Stanislav Kmoch, Aleš Hnízda, Martina Živná, Charles Pitts, Arielle Hay, Kateřina Hodaňová, Veronika Baresova, Viktor Stránecký, Blanka Stibůrková, Vaclava Skopova, Dita Musalkova, Anthony J. Bleyer, Hana Hartmannová, Dawn M. Wahezi, Olga Souckova
Publikováno v:
Rheumatology. 57:1180-1185
Objectives Phosphoribosylpyrophosphate synthetase (PRPS1) superactivity is an X-linked disorder characterized by urate overproduction Online Mendelian Inheritance in Man (OMIM) gene reference 300661. This condition is thought to rarely affect women,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de71824b68aa7a5fd43926287eab2e0c
https://doi.org/10.1093/rheumatology/key041
https://doi.org/10.1093/rheumatology/key041
Autor:
Lucie Andres Cerezo, Adéla Navrátilová, Hana Hulejová, Markéta Pavlíková, Jakub Závada, Karel Pavelka, Ladislav Šenolt, Blanka Stiburkova
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-7 (2023)
Abstract Objectives IL-37 is an anti-inflammatory cytokine involved in inflammatory and autoimmune diseases. We aimed to investigate the association between IL-37 genetic variants, IL-37 plasma levels, and various clinical phases of gout. Methods The
Externí odkaz:
https://doaj.org/article/0b397d3ce9954805b5cac16c05b19922