Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Blanka Kubešová"'
Autor:
Julian Baumeister, Lin Gan, Tiago Maié, Angela Maurer, Blanka Kubešová, Tim H. Brümmendorf, Andreas Schuppert, Nicolas Chatain, Barbora Weinbergerova, Marcelo A. S. Toledo, Deniz Gezer, Steffen Koschmieder, Zdenek Racil, Jiri Mayer, Ivan G. Costa, Jörg Eschweiler
Publikováno v:
Annals of hematology 100(12), 2943-2956 (2021). doi:10.1007/s00277-021-04615-8
Annals of Hematology
Annals of Hematology
Annals of hematology 100(12), 2943-2956 (2021). doi:10.1007/s00277-021-04615-8
Published by Springer, Berlin ; Heidelberg ; New York
Published by Springer, Berlin ; Heidelberg ; New York
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d124370f03a638a26ee0f7b73718ab06
https://doi.org/10.1007/s00277-021-04615-8
https://doi.org/10.1007/s00277-021-04615-8
Autor:
Daniela Zackova, Lukáš Semerád, Blanka Kubešová, Adam Folta, Jiri Mayer, Tomáš Jurček, Ivana Jeziskova
Publikováno v:
Leukemia & Lymphoma. 62:1239-1242
According to European Leukemia Network (ELN) recommendations, real-time quantitative PCR (qRT-PCR) is a conventional strategy for long-term BCR-ABL1 transcript monitoring in patients with chronic myeloid leukemia (CML) both during tyrosine kinase inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28b9ace940831b10dcf33677535aec5
https://doi.org/10.1080/10428194.2020.1861274
https://doi.org/10.1080/10428194.2020.1861274
Autor:
Susanne Isfort, Vera Kathrin Preußger, Ralf Weiskirchen, Walter Becker, Tim H. Brümmendorf, Kim Kricheldorf, Marlena Bütow, Stefan Tillmann, Mirle Schemionek, Blanka Kubešová, Nicolas Chatain, Jörg Eschweiler, Steffen Koschmieder, Martina Wessiepe, Barbora Weinbergerova, Jiri Mayer, Kathrin Olschok, Sarah K. Schröder, Milena Kalmer, Julian Baumeister, Zdenek Racil
Publikováno v:
Cancers
Cancers, Vol 13, Iss 4210, p 4210 (2021)
Cancers 13(16), 4210 (2021). doi:10.3390/cancers13164210 special issue: "Special Issue "Pathogenesis and Natural History of Myeloproliferative Neoplasms" / Special Issue Editor: Marco Pizzi, Guest Editor"
Volume 13
Issue 16
Cancers, Vol 13, Iss 4210, p 4210 (2021)
Cancers 13(16), 4210 (2021). doi:10.3390/cancers13164210 special issue: "Special Issue "Pathogenesis and Natural History of Myeloproliferative Neoplasms" / Special Issue Editor: Marco Pizzi, Guest Editor"
Volume 13
Issue 16
Lipocalin 2 (LCN2), a proinflammatory mediator, is involved in the pathogenesis of myeloproliferative neoplasms (MPN). Here, we investigated the molecular mechanisms of LCN2 overexpression in MPN. LCN2 mRNA expression was 20-fold upregulated in perip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b68400919e4bc9ee410a046fcf37d1
Autor:
Jiri Mayer, Hans Carl Hasselbalch, Zdenek Racil, Lijuan Han, Angela Maurer, Anders Lindholm Sørensen, Deniz Gezer, Claudia Schubert, Julia Czech, Ivan G. Costa, Sabrina Cordua, Tim H. Brümmendorf, Barbora Weinbergerova, Nicolas Chatain, Morten Orebo Holmström, Lasse Kjær, Trine Alma Knudsen, Bernd Denecke, Thomas Stauffer Larsen, Vibe Skov, Julian Baumeister, Steffen Koschmieder, Kristina Feldberg, Blanka Kubešová, Tiago Maié, Gerhard Müller-Newen, Assja Crepcia
Publikováno v:
Czech, J, Cordua, S, Weinbergerova, B, Baumeister, J, Crepcia, A, Han, L, Maié, T, Costa, I G, Denecke, B, Maurer, A, Schubert, C, Feldberg, K, Gezer, D, Brümmendorf, T H, Müller-Newen, G, Mayer, J, Racil, Z, Kubesova, B, Knudsen, T, Sørensen, A L, Holmström, M, Kjær, L, Skov, V, Larsen, T S, Hasselbalch, H C, Chatain, N & Koschmieder, S 2019, ' JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation ', Leukemia, vol. 33, no. 4, pp. 995-1010 . https://doi.org/10.1038/s41375-018-0295-6
Pegylated interferon-α (peg-IFNa) treatment induces molecular responses (MR) in patients with myeloproliferative neoplasms (MPNs), including partial MR (PMR) in 30–40% of patients. Here, we compared the efficacy of IFNa treatment in JAK2V617F- vs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f5523d5077aee3a85880cb282335b6
https://doi.org/10.1038/s41375-018-0295-6
https://doi.org/10.1038/s41375-018-0295-6
Autor:
Jitka Malčíková, Vojtech Bystry, Nikola Tom, Tobias Rausch, Miroslav Kolarik, Vladimir Benes, Šárka Pavlová, Ondrej Tom, Blanka Kubešová, Šárka Pospíšilová
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-9 (2018)
BMC Bioinformatics
BMC Bioinformatics
Background High-throughput bioinformatics analyses of next generation sequencing (NGS) data often require challenging pipeline optimization. The key problem is choosing appropriate tools and selecting the best parameters for optimal precision and rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57757ad1ceda3c07391c5e209801b338
http://link.springer.com/article/10.1186/s12859-018-2227-x
http://link.springer.com/article/10.1186/s12859-018-2227-x
Publikováno v:
Blood. 134:1646-1646
The detection and quantification of BCR-ABL1 transcripts play a key role in therapy management of chronic myeloid leukemia (CML) patients treated with tyrosine kinase inhibitors (TKIs). Reverse transcription quantitative PCR (RT-qPCR) is considered t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063658d376920d922a4eeac003421f4b
https://doi.org/10.1182/blood-2019-125551
https://doi.org/10.1182/blood-2019-125551
Autor:
Jiří Mayer, Barbara Kantorová, Jitka Malčíková, Miroslav Penka, Vojtech Bystry, Martina Sláviková, Šárka Pospíšilová, Jarmila Kissová, Michael Doubek, Lenka Radová, Robert Kralovics, Šárka Pavlová, Boris Tichy, Nikola Tom, Jitka Kabáthová, Bettina Gisslinger, Karla Plevová, Blanka Kubešová, Heinz Gisslinger, K Fiedorova
Publikováno v:
Leukemia
The multistep process of TP53 mutation expansion during myeloproliferative neoplasm (MPN) transformation into acute myeloid leukemia (AML) has been documented retrospectively. It is currently unknown how common TP53 mutations with low variant allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e8508b89931d7d9cfe5843c7f33b12
https://pubmed.ncbi.nlm.nih.gov/28744014
https://pubmed.ncbi.nlm.nih.gov/28744014
Autor:
Jana Kminkova, Ludmila Šebejová, Martin Trbušek, Jiri Mayer, Jana Zemanová, Michael Doubek, Blanka Kubešová, Yvona Brychtová, Veronika Navrkalová, Šárka Pospíšilová, Jana Šmardová
Publikováno v:
Blood. 120:3902-3902
Abstract 3902 Abnormalities of ATM gene are frequent in chronic lymphocytic leukemia (CLL) patients and represent important predictive and prognostic factor. ATM defects are commonly assessed through monitoring of 11q deletion (11q-) using I-FISH. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0776d57e774c44949772858621c28e9f
https://doi.org/10.1182/blood.v120.21.3902.3902
https://doi.org/10.1182/blood.v120.21.3902.3902
Autor:
Martin Trbušek, Jana Kminkova, Yvona Brychtová, Marek Mráz, Ludmila Šebejová, Veronika Navrkalová, Šárka Pospíšilová, Jitka Malčíková, Blanka Kubešová, Michael Doubek, Jiri Mayer, Jana Šmardová, Veronika Némethová, Jana Zemanová, David Potesil, Šárka Pavlová
Publikováno v:
Haematologica
ATM abnormalities are frequent in chronic lymphocytic leukemia and represent an important prognostic factor. Sole 11q deletion does not result in ATM inactivation by contrast to biallelic defects involving mutations. Therefore, the analysis of ATM mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd38f0dde17b357faf8f236c2944e85
The monograph Josef Dobrovský. Hungarologist and Finno-Ugrist deals not only with the strictly philological aspects of the Hungarologic and Finno-Ugric research of the founder of modern Slavic and Bohemistic studies Josef Dobrovsky, but also with hi