Discovery and characterization of small molecule inhibitors of the BET family bromodomains.

Autor: Chung CW; Molecular Discovery Research, GlaxoSmithKline R&D, Stevenage SG5 4HT, UK. Chun-Wa.H.Chung@gsk.com, Coste H, White JH, Mirguet O, Wilde J, Gosmini RL, Delves C, Magny SM, Woodward R, Hughes SA, Boursier EV, Flynn H, Bouillot AM, Bamborough P, Brusq JM, Gellibert FJ, Jones EJ, Riou AM, Homes P, Martin SL, Uings IJ, Toum J, Clement CA, Boullay AB, Grimley RL, Blandel FM, Prinjha RK, Lee K, Kirilovsky J, Nicodeme E

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2011 Jun 09; Vol. 54 (11), pp. 3827-38. Date of Electronic Publication: 2011 May 13.