Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Blanche Schroen"'
Autor:
Franziska Kenneweg, Claudia Bang, Ke Xiao, Chantal M. Boulanger, Xavier Loyer, Stephane Mazlan, Blanche Schroen, Steffie Hermans-Beijnsberger, Ariana Foinquinos, Marc N. Hirt, Thomas Eschenhagen, Sandra Funcke, Stevan Stojanovic, Celina Genschel, Katharina Schimmel, Annette Just, Angelika Pfanne, Kristian Scherf, Susann Dehmel, Stella M. Raemon-Buettner, Jan Fiedler, Thomas Thum
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 363-374 (2019)
Long non-coding RNAs (lncRNAs) have potential as novel therapeutic targets in cardiovascular diseases, but detailed information about the intercellular lncRNA shuttling mechanisms in the heart is lacking. Here, we report an important novel crosstalk
Externí odkaz:
https://doaj.org/article/082462a5ca7046e4a3a1e853a2b8ca0e
Autor:
Monika Rech, Annika R. Kuhn, Joost Lumens, Paolo Carai, Rick van Leeuwen, Wouter Verhesen, Robin Verjans, Julie Lecomte, Yilin Liu, Joost J.F.P. Luiken, Ronny Mohren, Berta Cillero-Pastor, Stephane Heymans, Kèvin Knoops, Marc van Bilsen, Blanche Schroen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 424-437 (2019)
MicroRNA-103/107 regulate systemic glucose metabolism and insulin sensitivity. For this reason, inhibitory strategies for these microRNAs are currently being tested in clinical trials. Given the high metabolic demands of the heart and the abundant ca
Externí odkaz:
https://doaj.org/article/03f5c125b05442e58d0707ee557c3fae
Publikováno v:
Non-coding RNA Research, Vol 3, Iss 3, Pp 118-130 (2018)
Following completion of the human genome, it became evident that the majority of our DNA is transcribed into non-coding RNAs (ncRNAs) instead of protein-coding messenger RNA. Deciphering the function of these ncRNAs, including both small- and long nc
Externí odkaz:
https://doaj.org/article/a1b1f6acdfce48b3b12cf80375a8e470
Autor:
Emma Louise Robinson, Clarissa Pedrosa da Costa Gomes, Ines Potočnjak, Jan Hellemans, Fay Betsou, David de Gonzalo-Calvo, Monika Stoll, Mehmet Birhan Yilmaz, Bence Ágg, Dimitris Beis, Maria Carmo-Fonseca, Francisco J. Enguita, Soner Dogan, Bilge G. Tuna, Blanche Schroen, Wim Ammerlaan, Gabriela M. Kuster, Irina Carpusca, Thierry Pedrazzini, Costanza Emanueli, Fabio Martelli, Yvan Devaux
Publikováno v:
Non-Coding RNA, Vol 6, Iss 2, p 17 (2020)
The EU-CardioRNA Cooperation in Science and Technology (COST) Action is a European-wide consortium established in 2018 with 31 European country members and four associate member countries to build bridges between translational researchers from academ
Externí odkaz:
https://doaj.org/article/4a44d6d94f9a4f628be3a1dfdb058072
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 262 (2020)
The adult mammalian heart is incapable of regeneration following cardiac injury, leading to a decline in function and eventually heart failure. One of the most evident barriers limiting cardiac regeneration is the inability of cardiomyocytes to divid
Externí odkaz:
https://doaj.org/article/5fa5a1b0a32240628939f44afeba19f9
Autor:
Chris McDermott-Roe, Marion Leleu, Glenn C Rowe, Oleg Palygin, John D Bukowy, Judy Kuo, Monika Rech, Steffie Hermans-Beijnsberger, Sebastian Schaefer, Eleonora Adami, Esther E Creemers, Matthias Heinig, Blanche Schroen, Zoltan Arany, Enrico Petretto, Aron M Geurts
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0170458 (2017)
Mitochondrial dysfunction contributes to myriad monogenic and complex pathologies. To understand the underlying mechanisms, it is essential to define the full complement of proteins that modulate mitochondrial function. To identify such proteins, we
Externí odkaz:
https://doaj.org/article/32ee4dc91d374bd4874942d7b45e8553
Autor:
Tim Peters, Steffie Hermans-Beijnsberger, Abdelaziz Beqqali, Nicole Bitsch, Shinichi Nakagawa, Kannanganattu V Prasanth, Leon J de Windt, Ralph J van Oort, Stephane Heymans, Blanche Schroen
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150236 (2016)
Long non-coding RNAs (lncRNAs) are a class of RNA molecules with diverse regulatory functions during embryonic development, normal life, and disease in higher organisms. However, research on the role of lncRNAs in cardiovascular diseases and in parti
Externí odkaz:
https://doaj.org/article/03a1e7f07452424a9bf3121042eda479
Autor:
Marjo M P C Donners, Ine M J Wolfs, Lauran J Stöger, Emiel P C van der Vorst, Chantal C H Pöttgens, Stephane Heymans, Blanche Schroen, Marion J J Gijbels, Menno P J de Winther
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35877 (2012)
microRNA-155 (miR155) is a central regulator of immune responses that is induced by inflammatory mediators. Although miR155 is considered to be a pro-inflammatory microRNA, in vitro reports show anti-inflammatory effects in lipid-loaded cells. In thi
Externí odkaz:
https://doaj.org/article/d93298f3a1cc40cfb5f1b6dc30024435
Autor:
Frans A. van Nieuwenhoven, Blanche Schroen, Lucio Barile, Lars van Middendorp, Frits W. Prinzen, Angelo Auricchio
Publikováno v:
Journal of Clinical Medicine. 12(2)
Cardiac resynchronization therapy (CRT) has become a valuable addition to the treatment options for heart failure, in particular for patients with disturbances in electrical conduction that lead to regionally different contraction patterns (dyssynchr
Autor:
Jenny E. Kootstra-Ros, Blanche Schroen, Laura M G Meems, Christian Mueller, Joan Walter, Stephan J. L. Bakker, Ron T. Gansevoort, Vanessa P. M. van Empel, Navin Suthahar, Pim van der Harst, Rudolf A. de Boer, Stephane Heymans, Dirk J. van Veldhuisen
Publikováno v:
Mayo clinic proceedings, 95(6), 1158-1168. ELSEVIER SCIENCE INC
Mayo Clinic Proceedings, 95(6), 1158-1168. Elsevier Science
Mayo Clinic Proceedings, 95(6), 1158-1168. Elsevier Science
Objective: To evaluate associations of high-sensitivity cardiac troponin-T (cTnT) with cardiovascular disease (CVD), heart failure (HF), and mortality in community-dwelling women and men. Participants and Methods: A total of 8226 adults from the Prev