Polarised cell intercalation during Drosophila axis extension is robust to an orthogonal pull by the invaginating mesoderm.

Autor: Lye CM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Blanchard GB; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Evans J; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Nestor-Bergmann A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Sanson B; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: PLoS biology [PLoS Biol] 2024 Apr 29; Vol. 22 (4), pp. e3002611. Date of Electronic Publication: 2024 Apr 29 (Print Publication: 2024).

Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation.

Autor: Fierling J; Univ. Grenoble Alpes, CNRS, LIPhy, 38000, Grenoble, France., John A; Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France., Delorme B; Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France., Torzynski A; Univ. Grenoble Alpes, CNRS, LIPhy, 38000, Grenoble, France., Blanchard GB; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, Great-Britain, England., Lye CM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, Great-Britain, England., Popkova A; Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France., Malandain G; Université Côte d'Azur, Inria, CNRS, I3S, Nice, France., Sanson B; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, Great-Britain, England., Étienne J; Univ. Grenoble Alpes, CNRS, LIPhy, 38000, Grenoble, France. Jocelyn.Etienne@univ-grenoble-alpes.fr., Marmottant P; Univ. Grenoble Alpes, CNRS, LIPhy, 38000, Grenoble, France., Quilliet C; Univ. Grenoble Alpes, CNRS, LIPhy, 38000, Grenoble, France., Rauzi M; Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France. Matteo.Rauzi@univ-cotedazur.fr.

Publikováno v: Nature communications [Nat Commun] 2022 Jun 10; Vol. 13 (1), pp. 3348. Date of Electronic Publication: 2022 Jun 10.

Correct regionalization of a tissue primordium is essential for coordinated morphogenesis.

Autor: Sánchez-Corrales YE; MRC Laboratory of Molecular Biology,Cambridge Biomedical Campus, Cambridge, United Kingdom.; Genetics and Genomic Medicine Programme, Institute of Child Health, University College London, London, United Kingdom., Blanchard GB; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Röper K; MRC Laboratory of Molecular Biology,Cambridge Biomedical Campus, Cambridge, United Kingdom.

Publikováno v: ELife [Elife] 2021 Nov 01; Vol. 10. Date of Electronic Publication: 2021 Nov 01.

Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.

Autor: Moreno L; Paediatric Haematology & Oncology Division, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Electronic address: lucas.moreno@vhebron.net., Barone G; Department of Paediatric Oncology, Great Ormond Street Hospital for Children, London, UK., DuBois SG; Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA, USA., Molenaar J; Princess Máxima Centre for Paediatric Oncology, Utrecht, The Netherlands., Fischer M; Experimental Pediatric Oncology, University Children's Hospital, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne, Cologne, Germany., Schulte J; Department of Pediatric Oncology & Hematology, Charité University Hospital, Berlin, Germany., Eggert A; Department of Pediatric Oncology & Hematology, Charité University Hospital, Berlin, Germany; German Cancer Consortium (DKTK Berlin), Berlin, Germany; Berlin Institute of Health (BIH), Berlin, Germany., Schleiermacher G; SIREDO, Department of Paediatric, Adolescents and Young Adults Oncology and INSERM U830, Institut Curie, Paris, France., Speleman F; Center for Medical Genetics Ghent (CMGG), Department of Biomolecular Medicine, Cancer Research Institute Ghent (CRIG), Belgium., Chesler L; Paediatric Drug Development, Children & Young People's Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK; Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK., Geoerger B; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, University Paris-Saclay & Inserm U1015, Villejuif, France., Hogarty MD; Division of Oncology, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania, USA; Perelman School of Medicine, University of Pennsylvania, USA., Irwin MS; Department of Paediatrics, Medical Biophysics and Laboratory Medicine & Pathobiology, The Hospital for Sick Kids, Toronto, Canada., Bird N; Solving Kids' Cancer, UK and National Cancer Research Institute Children's Cancer & Leukaemia Clinical Studies Group, UK., Blanchard GB; Neuroblastoma UK & Department of Physiology, Development & Neuroscience, University of Cambridge, UK., Buckland S; Pfizer Ltd, Surrey, UK., Caron H; Hoffmann-La Roche Ltd, Basel, Switzerland., Davis S; Cyclacel Limited, Dundee, UK., De Wilde B; Center for Medical Genetics Ghent (CMGG), Department of Biomolecular Medicine, Cancer Research Institute Ghent (CRIG), Belgium., Deubzer HE; Center for Molecular Medicine Cologne (CMMC), Medical Faculty, University of Cologne, Cologne, Germany., Dolman E; Department of Translational Research, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands., Eilers M; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Germany., George RE; Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Harvard Medical School, Boston, MA, USA., George S; Paediatric Drug Development, Children & Young People's Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK; Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK., Jaroslav Š; Pediatric Oncology Department, University Hospital Brno, School of Medicine Masaryk University Brno, Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, ICRC Brno, St Anna University Hospital Brno, Czech Republic., Maris JM; Division of Oncology, Children's Hospital of Philadelphia and Department of Pediatrics, University of Pennsylvania, USA; Perelman School of Medicine, University of Pennsylvania, USA., Marshall L; Paediatric Drug Development, Children & Young People's Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK; Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK., Merchant M; Astrazeneca, Early Clinical Projects, Oncology Translation Medicines Unit, Innovative Medicines Unit, Cambridge, UK., Mortimer P; Astrazeneca, Early Clinical Projects, Oncology Translation Medicines Unit, Innovative Medicines Unit, Cambridge, UK., Owens C; Department of Paediatric Haemaology/Oncology, Our Lady's Children's Hospital, Dublin, Ireland., Philpott A; Department of Oncology, University of Cambridge, UK., Poon E; Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK., Shay JW; Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX, USA., Tonelli R; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy., Valteau-Couanet D; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, University Paris-Saclay & Inserm U1015, Villejuif, France., Vassal G; Department of Clinical Research, Gustave Roussy, Paris-Sud University, Paris, France., Park JR; Department of Pediatrics, University of Washington School of Medicine and Center for Clinical and Translational Research, Seattle Children's Hospital, USA., Pearson ADJ; Paediatric Drug Development, Children & Young People's Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK; Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, Sutton, UK.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2020 Sep; Vol. 136, pp. 52-68. Date of Electronic Publication: 2020 Jul 09.

The tricellular vertex-specific adhesion molecule Sidekick facilitates polarised cell intercalation during Drosophila axis extension.

Autor: Finegan TM; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Hervieux N; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Nestor-Bergmann A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Fletcher AG; School of Mathematics and Statistics, University of Sheffield, Sheffield, United Kingdom.; Bateson Centre, University of Sheffield, Sheffield, United Kingdom., Blanchard GB; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom., Sanson B; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: PLoS biology [PLoS Biol] 2019 Dec 05; Vol. 17 (12), pp. e3000522. Date of Electronic Publication: 2019 Dec 05 (Print Publication: 2019).