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Acquired hemophilia as the cause of life-threatening hemorrhage in a 94-year-old man: a case report

Autor: Blanchard Elizabeth, Raphael Jonelle, Kelesidis Theodoros, Parameswaran Rekha

Publikováno v: Journal of Medical Case Reports, Vol 4, Iss 1, p 231 (2010)

Abstract Introduction Acquired factor VIII deficiency is a rare entity that can lead to severe and life-threatening bleeding. We describe a case of severe bleeding from the tongue secondary to acquired hemophilia and discuss treatment options, includ

Externí odkaz: https://doaj.org/article/11774b21af47406fa756a478dd7fc89c

Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents.

Autor: Blanchard EL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Vanover D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Bawage SS; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Tiwari PM; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Rotolo L; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Beyersdorf J; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Peck HE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Bruno NC; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Hincapie R; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Michel F; Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine University of Georgia, Athens, GA, USA., Murray J; Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, GA, USA., Sadhwani H; Department of Biology, Georgia State University, Atlanta, GA, USA., Vanderheyden B; Analytics and Data Science Institute, Kennesaw State University, Kennesaw, GA, USA., Finn MG; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA, USA., Brinton MA; Department of Biology, Georgia State University, Atlanta, GA, USA., Lafontaine ER; Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, GA, USA., Hogan RJ; Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine University of Georgia, Athens, GA, USA.; Department of Infectious Diseases, College of Veterinary Medicine University of Georgia, Athens, GA, USA., Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA. chiara@gatech.edu., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA. philip.santangelo@bme.gatech.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2021 Jun; Vol. 39 (6), pp. 717-726. Date of Electronic Publication: 2021 Feb 03.

TRAF6-IRF5 kinetics, TRIF, and biophysical factors drive synergistic innate responses to particle-mediated MPLA-CpG co-presentation.

Autor: Pradhan P; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.; The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.; Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology, Atlanta, GA, USA., Toy R; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Jhita N; Lowance Center of Human Immunology, Department of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, GA, USA., Atalis A; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Pandey B; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Beach A; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Blanchard EL; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Moore SG; The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA., Gaul DA; The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA., Santangelo PJ; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Shayakhmetov DM; Lowance Center of Human Immunology, Department of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, GA, USA.; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Roy K; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA. krish.roy@gatech.edu.; The Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA, USA.; Marcus Center for Therapeutic Cell Characterization and Manufacturing, Georgia Institute of Technology, Atlanta, GA, USA.

Publikováno v: Science advances [Sci Adv] 2021 Jan 13; Vol. 7 (3). Date of Electronic Publication: 2021 Jan 13 (Print Publication: 2021).

Increased PIP3 activity blocks nanoparticle mRNA delivery.

Autor: Paunovska K; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Da Silva Sanchez A; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Foster MT; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Loughrey D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Blanchard EL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Islam FZ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Gan Z; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Mantalaris A; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Dahlman JE; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Publikováno v: Science advances [Sci Adv] 2020 Jul 22; Vol. 6 (30), pp. eaba5672. Date of Electronic Publication: 2020 Jul 22 (Print Publication: 2020).