Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Blance, Rognvald"'
Autor:
Pearson, Stella1 (AUTHOR), Blance, Rognvald1 (AUTHOR), Yan, Fei2,3 (AUTHOR), Hsieh, Ya-Ching2,3 (AUTHOR), Geary, Bethany4 (AUTHOR), Amaral, Fabio M. R.5 (AUTHOR), Somervaille, Tim C. P.5 (AUTHOR), Kirschner, Kristina2,3 (AUTHOR), Whetton, Anthony D.1 (AUTHOR), Pierce, Andrew1 (AUTHOR) A.Pierce@Bangor.ac.uk
Publikováno v:
PLoS ONE. 5/30/2023, Vol. 17 Issue 5, p1-16. 16p.
Autor:
Richardson, Rose, Mitchell, Karen, Hammond, Nigel, Mollo, Maria Rosaria, Kouwenhoven, Evelyn N., Wyatt, Niki, Donaldson, Ian, Zeef, Leo, Burgis, Timothy, Blance, Rognvald, van Heeringen, Simon J., Stunnenberg, Hendrik G, Zhou, Huiqing, Missero, Caterina, Romano, Rose Anne, Sinha, Satrajit, Dixon, Michael, Dixon, Jill
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006828 (2017)
PLoS Genetics
Richardson, R, Mitchell, K, Hammond, N, Mollo, M R, Kouwenhoven, E N, Wyatt, N, Donaldson, I, Zeef, L, Burgis, T, Blance, R, van Heeringen, S J, Stunnenberg, H G, Zhou, H, Missero, C, Romano, R A, Sinha, S, Dixon, M & Dixon, J 2017, ' p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate ', PL o S Genetics, vol. 13, no. 6, e1006828 . https://doi.org/10.1371/journal.pgen.1006828
PLoS Genetics
Richardson, R, Mitchell, K, Hammond, N, Mollo, M R, Kouwenhoven, E N, Wyatt, N, Donaldson, I, Zeef, L, Burgis, T, Blance, R, van Heeringen, S J, Stunnenberg, H G, Zhou, H, Missero, C, Romano, R A, Sinha, S, Dixon, M & Dixon, J 2017, ' p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate ', PL o S Genetics, vol. 13, no. 6, e1006828 . https://doi.org/10.1371/journal.pgen.1006828
Cleft palate is a common congenital disorder that affects up to 1 in 2500 live births and results in considerable morbidity to affected individuals and their families. The aetiology of cleft palate is complex with both genetic and environmental facto
Akademický článek
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Autor:
Pearson, Stella, Williamson, Andrew, Blance, Rognvald, Somervaille, Timothy, Taylor, Samuel, Azadbakht, Narges, Whetton, Anthony, Pierce, Andrew
Publikováno v:
Pearson, S, Williamson, A, Blance, R, Somervaille, T, Taylor, S, Azadbakht, N, Whetton, A & Pierce, A 2017, ' Proteomic analysis of JAK2V617F induced changes identifies 2 potential new combinatorial therapeutic approaches ', Leukemia . https://doi.org/10.1038/leu.2017.143
In excess of 90% of patients with polycythaemia vera (PV) express a mutated form of Janus kinase 2 (JAK2), JAK2V617F. Such aberrant proteins offer great potential for the treatment of these diseases; however, inhibitors to JAK2 have had limited succe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::b64c47dd69108ccdd7a97c94016c74ac
https://doi.org/10.1038/leu.2017.143
https://doi.org/10.1038/leu.2017.143
Autor:
Whetton, Anthony D, Azmi, Norhaida Che, Pearson, Stella, Jaworska, Ewa, Zhang, Liqun, Blance, Rognvald, Kendall, Alexandra C, Nicolaou, Anna, Taylor, Samuel, Williamson, Andrew J K, Pierce, Andrew
Publikováno v:
Whetton, A D, Azmi, N C, Pearson, S, Jaworska, E, Zhang, L, Blance, R, Kendall, A C, Nicolaou, A, Taylor, S, Williamson, A J K & Pierce, A 2016, ' MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5 ', Oncotarget, vol. 7, no. 10, pp. 10739-55 . https://doi.org/10.18632/oncotarget.7639
The thrombopoietin receptor (MPL) has been shown to be mutated (MPL W515L) in myelofibrosis and thrombocytosis yet new approaches to treat this disorder are still required. We have previously shown that transcriptome and proteomic effects do not corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::b894440e12a6cf11b363fa6bb15b4592
https://www.research.manchester.ac.uk/portal/en/publications/mpl-w515l-expression-induces-tgf-secretion-and-leads-to-an-increase-in-chemokinesis-via-phosphorylation-of-thoc5(c13f2e2e-badd-47ef-a2a1-e107b30c3d46).html
https://www.research.manchester.ac.uk/portal/en/publications/mpl-w515l-expression-induces-tgf-secretion-and-leads-to-an-increase-in-chemokinesis-via-phosphorylation-of-thoc5(c13f2e2e-badd-47ef-a2a1-e107b30c3d46).html
Akademický článek
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Akademický článek
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Autor:
Whetton AD; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Azmi NC; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Pearson S; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Jaworska E; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Zhang L; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Blance R; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Kendall AC; Manchester Pharmacy School, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK., Nicolaou A; Manchester Pharmacy School, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK., Taylor S; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Williamson AJ; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK., Pierce A; Stem Cell and Leukaemia Proteomics Laboratory, The University of Manchester, Manchester, UK.
Publikováno v:
Oncotarget [Oncotarget] 2016 Mar 08; Vol. 7 (10), pp. 10739-55.