The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas

Autor: Humberto García-Ortiz, Francisco Barajas-Olmos, Cecilia Contreras-Cubas, Miguel Ángel Cid-Soto, Emilio J. Córdova, Federico Centeno-Cruz, Elvia Mendoza-Caamal, Isabel Cicerón-Arellano, Marlen Flores-Huacuja, Paulina Baca, Deborah A. Bolnick, Meradeth Snow, Silvia Esperanza Flores-Martínez, Rocio Ortiz-Lopez, Austin W. Reynolds, Antonio Blanchet, Mirna Morales-Marín, Rafael Velázquez-Cruz, Aleksandar David Kostic, Carlos Galaviz-Hernández, Alejandra Guadalupe García-Zapién, José Concepción Jiménez-López, Guadalupe León-Reyes, Eva Gabriela Salas-Bautista, Blanca Patricia Lazalde-Ramos, Juan Luis Jiménez-Ruíz, Guadalupe Salas-Martínez, Jazmín Ramos-Madrigal, Elaheh Mirzaeicheshmeh, Yolanda Saldaña-Alvarez, María del Carmen Abrahantes-Pérez, Francisco Loeza-Becerra, Raúl Mojica-Espinosa, Federico Sánchez-Quinto, Héctor Rangel-Villalobos, Martha Sosa-Macías, José Sánchez-Corona, Augusto Rojas-Martinez, Angélica Martínez-Hernández, Lorena Orozco

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geogr

Externí odkaz: https://doaj.org/article/c86ceb211f3846cf9fd37b70fafef48a

Evaluation of Genotoxic Effect and Antigenotoxic Potential against DNA Damage of the Aqueous and Ethanolic Leaf Extracts of Annona muricata Using an In Vivo Erythrocyte Rodent Micronucleus Assay

Autor: Susana Vanessa Sánchez-De-La-Rosa, Blanca Patricia Lazalde-Ramos, Gabriela Morales-Velazquez, Guillermo Moisés Zúñiga-González, Belinda Claudia Gómez-Meda, Saulo Oswaldo Sánchez-Rivera, Yveth Marlene Ortiz-García, Celia Guerrero-Velazquez, Ana Lourdes Zamora-Perez

Publikováno v: BioMed Research International. 2022:1-15

Annona muricata have been extensively used in traditional medicine to treat multiple diseases, including cancers. This study evaluated the genotoxic potential and antigenotoxic activities of A. muricata aqueous and ethanolic leaf extracts by employin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fa6337e5a22017f91633b2bf6ee8d0
https://doi.org/10.1155/2022/9554011

Cytotoxic and Genotoxic Evaluation of the Aqueous and Hydroalcoholic Leaf and Bark Extracts of Crataegus oxyacantha in Murine Model

Autor: Fany Renata Aguilera-Rodríguez, Ana Lourdes Zamora-Perez, Clara Luz Galván-Moreno, Rosalinda Gutiérrez-Hernández, Claudia Araceli Reyes Estrada, Edgar L. Esparza-Ibarra, Blanca Patricia Lazalde-Ramos

Publikováno v: Plants, Vol 10, Iss 10, p 2217 (2021)

Crataegus oxyacantha has been mainly used in traditional medicine for the treatment of cardiovascular diseases. However, its safety profile has not been fully established, since only the genotoxic effects of C. oxyacantha fruit have been described. T

Externí odkaz: https://doaj.org/article/3c7b1788f48a4416921a509eb2e050f4

Paternal Determinants in Preeclampsia

Autor: Carlos Galaviz-Hernandez, Martha Sosa-Macias, Enrique Teran, Jose Elias Garcia-Ortiz, Blanca Patricia Lazalde-Ramos

Publikováno v: Frontiers in Physiology, Vol 9 (2019)

Preeclampsia is a condition associated with high rates of maternal-fetal morbidity and mortality. It usually occurs in 3–10% of nulliparous women and 18% of previously affected women. Different lines of evidence have demonstrated the role of the fa

Externí odkaz: https://doaj.org/article/61db0bd8e01e4eba99ef4797853d6ba9

Unraveling Signatures of Local Adaptation among Indigenous Groups from Mexico

Autor: Humberto García-Ortiz, Francisco Barajas-Olmos, Cecilia Contreras-Cubas, Austin W. Reynolds, Marlen Flores-Huacuja, Meradeth Snow, Jazmín Ramos-Madrigal, Elvia Mendoza-Caamal, Paulina Baca, Tomás A. López-Escobar, Deborah A. Bolnick, Silvia Esperanza Flores-Martínez, Rocio Ortiz-Lopez, Aleksandar David Kostic, José Rafael Villafan-Bernal, Carlos Galaviz-Hernández, Federico Centeno-Cruz, Alejandra Guadalupe García-Zapién, Tulia Monge-Cázares, Blanca Patricia Lazalde-Ramos, Francisco Loeza-Becerra, María del Carmen Abrahantes-Pérez, Héctor Rangel-Villalobos, Martha Sosa-Macías, Augusto Rojas-Martínez, Angélica Martínez-Hernández, Lorena Orozco

Publikováno v: García-Ortiz, H, Barajas-Olmos, F, Contreras-Cubas, C, Reynolds, A W, Flores-Huacuja, M, Snow, M, Ramos-Madrigal, J, Mendoza-Caamal, E, Baca, P, López-Escobar, T A, Bolnick, D A, Flores-Martínez, S E, Ortiz-Lopez, R, Kostic, A D, Villafan-Bernal, J R, Galaviz-Hernández, C, Centeno-Cruz, F, García-Zapién, A G, Monge-Cázares, T, Lazalde-Ramos, B P, Loeza-Becerra, F, Abrahantes-Pérez, M D C, Rangel-Villalobos, H, Sosa-Macías, M, Rojas-Martínez, A, Martínez-Hernández, A & Orozco, L 2022, ' Unraveling Signatures of Local Adaptation among Indigenous Groups from Mexico ', Genes, vol. 13, no. 12, 2251 . https://doi.org/10.3390/genes13122251
Genes; Volume 13; Issue 12; Pages: 2251

Few studies have addressed how selective pressures have shaped the genetic structure of the current Native American populations, and they have mostly limited their inferences to admixed Latin American populations. Here, we searched for local adaptati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582cc5cfbbaa9739844efe68ce19ed6b
https://curis.ku.dk/portal/da/publications/unraveling-signatures-of-local-adaptation-among-indigenous-groups-from-mexico(fb6e64a2-de12-4175-9651-cebccd315367).html