Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Blanca Ostmark"'
Publikováno v:
Cytometry Part B: Clinical Cytometry. :281-289
Background: We have been interested in studying the roles of two aldehyde dehydrogenases in the biology of lung cancer. In this study, we seek to apply Aldefluor flow cytometry-based assay for the measurement of aldehyde dehydrogenase (ALDH) activity
Publikováno v:
Cancer Chemotherapy and Pharmacology. 59:127-136
Purpose: Aldehyde dehydrogenases class-1A1 (ALDH1A1) and class-3A1 (ALDH3A1) have been associated with resistance to cyclophosphamide (CP) and its derivatives. We have previously reported the downregulation of these enzymes by all-trans retinoic acid
Autor:
John K. Amory, Jan S. Moreb, Alex S. Goldstein, Lung-Ji Chang, Shuhong Han, Deniz A. Ucar, Blanca Ostmark
Publikováno v:
Chemico-biological interactions. 195(1)
There has been a new interest in using aldehyde dehydrogenase (ALDH) activity as one marker for stem cells since the Aldefluor flow cytometry-based assay has become available. Diethylaminobenzaldehyde (DEAB), used in the Aldeflour assay, has been con
Autor:
Lung-Ji Chang, Blanca Ostmark, Wayne Chou, Henry V. Baker, M. Cecilia Lopez, Jan S. Moreb, Maria Amaya
Publikováno v:
Molecular Cancer, Vol 7, Iss 1, p 87 (2008)
Molecular Cancer
Molecular Cancer
Background Aldehyde dehydrogenase isozymes ALDH1A1 and ALDH3A1 are highly expressed in non small cell lung cancer. Neither the mechanisms nor the biologic significance for such over expression have been studied. Methods We have employed oligonucleoti
Autor:
Brian A. Gray, Edward W. Scott, Christopher R. Cogle, Jan S. Moreb, James R. Zucali, Robert Zori, Deniz A. Ucar, Blanca Ostmark
Publikováno v:
Chemico-biological interactions. 178(1-3)
Aldehyde dehydrogenase (ALDH) activity has been implicated in multiple biological and biochemical pathways and has been used to identify potential cancer stem cells. Our main hypothesis is that ALDH activity may be a lung cancer stem cell marker. Usi
Publikováno v:
Cancer Research. 70:3362-3362
With the cancer stem cell theory, there has been an invigorated new interest in finding more markers for stem cells. Aldehdye dehydrogenase (ALDH) is one such marker that became popular since a flow cytometry based assay, Aldeflour staining, has beco