Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Blanca Martinez-Teipel"'
Autor:
Patrick J. Carroll, Pamela R. Seida, Mathieu Michaut, Alison L. Muller, Roland E. Dolle, Robert N. DeHaven, Christopher W. Ajello, Blanca Martinez-Teipel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:3647-3650
Cyclic tetrapeptide c[Phe-pro-Phe-trp] 2, a diastereomer of CJ-15,208 (1), was identified as a potent dual kappa/mu opioid receptor antagonist devoid of delta opioid receptor affinity against cloned human receptors: K(i) (2)=3.8nM (kappa), 30nM (mu);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ceebfdc49e6c33d085494bccaf4d0d
https://doi.org/10.1016/j.bmcl.2009.04.105
https://doi.org/10.1016/j.bmcl.2009.04.105
Publikováno v:
Journal of Combinatorial Chemistry. 8:132-140
The microwave-assisted solid-phase synthesis of piperazines, 3,9-diazaspiro[5.5]undecanes and 2,9-diazaspiro[5.5]undecanes is reported. The synthesis relies on the direct annulation of primary amines with resin-bound bismesylates 12, 17, and 22. Crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2d8966744b7da2881a7a751a694d1e
https://doi.org/10.1021/cc050106w
https://doi.org/10.1021/cc050106w
Autor:
Pamela R. Seida, William M. Barker, Calum Macleod, Torsten Herbertz, Roland E. Dolle, Blanca Martinez-Teipel
Publikováno v:
Angewandte Chemie. 117:5980-5983
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057a2ef80746c7f229fa1f1b6bb56dd7
https://doi.org/10.1002/ange.200501665
https://doi.org/10.1002/ange.200501665
Publikováno v:
QSAR & Combinatorial Science. 23:854-858
The microwave-assisted, parallel synthesis of di- and trisubstituted ureas is described. Microwave irradiation provides a significant rate enhancement to the in situ thermolytic cleavage of isocyanates from polymer-supported carbamates. The method is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2472c72397a0f0f2eed67fbdabc501a7
https://doi.org/10.1002/qsar.200420043
https://doi.org/10.1002/qsar.200420043
Autor:
Mathieu Machaut, Joel A. Cassel, Gabriel J. Stabley, Robert N. DeHaven, Roland E. Dolle, Thomas M. Graczyk, Blanca Martinez-Teipel, Serge Belanger
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:3545-3548
( S )-4-(Carboxamido)phenylalanine (Cpa) is examined as a bioisosteric replacement for the terminal tyrosine (Tyr) residue in a variety of known peptide ligands for the μ , δ , and κ opioid receptors. The Cpa-containing peptides, assayed against c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63288140e896f649e1bebb0082a4e2f1
https://doi.org/10.1016/j.bmcl.2004.04.039
https://doi.org/10.1016/j.bmcl.2004.04.039
Autor:
Mark J. Mulvihill, Damian Gerard Weaver, Rhoda Weber Joseph, Arkady Gusev, William Dean Mathis, Brian S. MacDougall, Duyan V. Nguyen, KiHo Chung, James C. Gallagher, Blanca Martinez-Teipel
Publikováno v:
Tetrahedron Letters. 42:7751-7754
The synthesis of a series of substituted benzaldehyde-derived chloroformates and their application towards the synthesis of a diverse series of novel insecticidally active carboxylic acid [ N ′- tert -butyl- N ′-(3,5-dimethylbenzoyl)- N -(3-metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1123ec7d868f2ceb71d1e217b26128f3
https://doi.org/10.1016/s0040-4039(01)01644-6
https://doi.org/10.1016/s0040-4039(01)01644-6
Autor:
M. T. Copete, A. Llimargas, Jordi Teixidó, E. Garcia, Josep Lluis Matallana, Blanca Martinez-Teipel, José I. Borrell
Publikováno v:
Journal of Medicinal Chemistry. 41:3539-3545
The 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7, 8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7, 8-tetrahydrofolic acid (DDATHF) were synthesized as potential antifolates. Treatment of the alpha,beta-unsaturated esters 11a-c, obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ef53e1bddaf739ebd3bae2e530e928
https://doi.org/10.1021/jm9801298
https://doi.org/10.1021/jm9801298
Autor:
Marta Costa, Blanca Serra, Xavier Batllori, Josep Lluis Matallana, Blanca Martinez-Teipel, José I. Borrell, Jordi Teixidó
Publikováno v:
Collection of Czechoslovak Chemical Communications. 61:901-909
An unequivocal set of procedures for the synthesis of 4-amino-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-2,7-diones (7) and 2-amino-3,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-4,7-diones (8), in a maximum of four steps from an α,β-unsaturated ester 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a0fbc6bd6a37c941635383ac1e824a0
https://doi.org/10.1135/cccc19960901
https://doi.org/10.1135/cccc19960901
Autor:
José I. Borrell, Youbang Liu, Shushi Chen, Daniel W. Armstrong, Josep Lluis Matallana, Blanca Martinez-Teipel
Publikováno v:
Journal of Liquid Chromatography. 18:1495-1507
Nine different 4−, or 5− substituted racemic pyridones were synthesized and resolved by reversed phase LC. Seven of the compounds showed complete or partial resolution on the vancomycin bonded phase column, while five compounds each were separate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4966e00b061df5910ca21beff1a908f
https://doi.org/10.1080/10826079508009290
https://doi.org/10.1080/10826079508009290
Autor:
M. Costa, Jordi Teixidó, Xavier Batllori, Blanca Martinez-Teipel, Blanca Serra, José I. Borrell, Josep Lluis Matallana
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::283f9656421c176c759184628abdfb23
https://doi.org/10.1002/chin.199639178
https://doi.org/10.1002/chin.199639178