Zobrazeno 1 - 10
of 861
pro vyhledávání: '"Blanca Lopez"'
Autor:
Ann Schirin Mirsanaye, Saskia Hoffmann, Melanie Weisser, Andreas Mund, Blanca Lopez Mendez, Dimitris Typas, Johannes van den Boom, Bente Benedict, Ivo A. Hendriks, Michael Lund Nielsen, Hemmo Meyer, Julien P. Duxin, Guillermo Montoya, Niels Mailand
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The hexameric AAA+ ATPase p97/VCP functions as an essential mediator of ubiquitin-dependent cellular processes, extracting ubiquitylated proteins from macromolecular complexes or membranes by catalyzing their unfolding. p97 is directed to ub
Externí odkaz:
https://doaj.org/article/94acc0facb2c40838b11f84474d25e74
Autor:
Elena Panizo-Morgado, Felisa Vazquez-Gómez, Marta Perez-Somarriba, Miriam Pavon-Mengual, Andrés Morales-La Madrid, Blanca Lopez-Ibor, Palma Solano, Blanca Martinez de las Heras, Marta Cortés-Hernández, Miguel García-Ariza, Roberto Carlos Raynero-Mellado, Marta Martinez-Merino, Ana de Lucio Delgado, María Tallón-García, Carmen Garrido-Colino, Irene Ortiz-Gonzalez, Raquel Portugal, María Baro-Fernández, Carmen Gonzalez San-Segundo, Felipe Calvo, Alvaro Lassaletta
Publikováno v:
EJC Paediatric Oncology, Vol 4, Iss , Pp 100183- (2024)
Introduction: Diffuse intrinsic pontine glioma (DIPG) is the most common malignant brainstem tumour in children. Despite advances in understanding its biology, current treatments have shown minimal impact on overall survival in this fatal disease. Fo
Externí odkaz:
https://doaj.org/article/ce7f149b3aea42b3b217a1539e1170f3
Autor:
Alicia Mora, Adrian Prados, Alberto Mendez, Gonzalo Espinoza, Pavel Gonzalez, Blanca Lopez, Victor Muñoz, Luis Moreno, Santiago Garrido, Ramon Barber
Publikováno v:
Frontiers in Neurorobotics, Vol 18 (2024)
One of the major problems of today's society is the rapid aging of its population. Life expectancy is increasing, but the quality of life is not. Faced with the growing number of people who require cognitive or physical assistance, new technological
Externí odkaz:
https://doaj.org/article/f383d654d3794e53995f2e16addf469a
Autor:
Jamin B Hein, Hieu T Nguyen, Dimitriya H Garvanska, Isha Nasa, Thomas Kruse, Yinnian Feng, Blanca Lopez Mendez, Norman Davey, Arminja N Kettenbach, Polly M Fordyce, Jakob Nilsson
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract Phosphoprotein phosphatases (PPPs) regulate major signaling pathways, but the determinants of phosphatase specificity are poorly understood. This is because methods to investigate this at scale are lacking. Here, we develop a novel in vitro
Externí odkaz:
https://doaj.org/article/2b7f9cdcf70344a5bb703577c2b23118
Autor:
Mustika Rahmawati, Kassie M. Stadler, Blanca Lopez-Biladeau, Tia M. Hoisington, Nathan C. Law
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Much of the foundation for lifelong spermatogenesis is established prior to puberty, and disruptions during this developmental window negatively impact fertility long into adulthood. However, the factors that coordinate prepubertal germline developme
Externí odkaz:
https://doaj.org/article/0c380bd59153467bacca54ba2acd3645
Publikováno v:
Applied Sciences, Vol 14, Iss 3, p 1018 (2024)
Quantum technologies promise major advances in different areas. From computation to sensing or telecommunications, quantum implementations could bring significant improvements to these fields, arousing the interest of researchers, companies, and gove
Externí odkaz:
https://doaj.org/article/b932e0cd3bca495baeb531ab1dec225d
Autor:
Sara M. Ambjørn, Julien P. Duxin, Emil P. T. Hertz, Isha Nasa, Joana Duro, Thomas Kruse, Blanca Lopez-Mendez, Beata Rymarczyk, Lauren E. Cressey, Thomas van Overeem Hansen, Arminja N. Kettenbach, Vibe H. Oestergaard, Michael Lisby, Jakob Nilsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
BRCA2 plays a central role in facilitating DNA repair by homologous recombination (HR). Here the authors describe how BRCA2 forms a complex with the protein phosphatase PP2A-B56 in response to DNA damage, which is required for HR.
Externí odkaz:
https://doaj.org/article/79b0e8134f2045ccac494a8dddce3e54
Autor:
Ario de Marco, Nick Berrow, Mario Lebendiker, Maria Garcia-Alai, Stefan H. Knauer, Blanca Lopez-Mendez, André Matagne, Annabel Parret, Kim Remans, Stephan Uebel, Bertrand Raynal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents sh
Externí odkaz:
https://doaj.org/article/51ce73ae195442a99d981f1a7543b04b
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The BubR1/Bub3 complex regulates chromosome segregation to enable proper kinetochore-microtubule interactions and is also required for the spindle assembly checkpoint. Here the authors show that two distinct pools of BubR1/Bub3 exist at kinetochores
Externí odkaz:
https://doaj.org/article/683703f88b40405d9999b5a8529ec761
Autor:
Muñoz-Gómez, María José, Ryan, Pablo, Quero-Delgado, Marta, Martin-Vicente, María, Cuevas, Guillermo, Valencia, Jorge, Jiménez, Eva, Blanca-López, Natalia, Lara-Álvarez, Miguel Ángel, Hernández-Rivas, José Ángel, Redondo, Gerardo, Mas, Vicente, Sepúlveda-Crespo, Daniel, Vázquez, Mónica, Torres-Macho, Juan, Martínez, Isidoro, Resino, Salvador
Publikováno v:
In Journal of Infection and Public Health July 2024 17(7)