Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Blanca Ledezma"'
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
We retrospectively analyzed non–small cell lung cancer (NSCLC) patients from a single center treated with pembrolizumab on the KEYNOTE-001 trial and evaluated the association between treatment-related adverse events (trAEs) and clinical outcomes. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b3b7874e10d49b2182ef37d7bfcab0
https://doi.org/10.1158/2326-6066.c.6549188.v1
https://doi.org/10.1158/2326-6066.c.6549188.v1
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Table S2: Demographics of the 97 NSCLC patients treated at UCLA on KEYNOTE-001 (N=97) compared with the demographics of the total KEYNOTE-001 study population (n=495). Of note, the UCLA cohort of 97 patients is included in the total KEYNOTE-001 study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac38894d1c0e7b0541133ec22e2e4172
https://doi.org/10.1158/2326-6066.22539803
https://doi.org/10.1158/2326-6066.22539803
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Table S3: The occurrence of a treatment related AE (trAE) in the 97 patients treated at UCLA on the KEYNOTE-001 clinical trial, stratified by a history of thoracic radiation therapy (TRT) or prior radiation therapy to any location. P values computed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cfb588d202a63e3b24a85a8d4a8dd6
https://doi.org/10.1158/2326-6066.22539800
https://doi.org/10.1158/2326-6066.22539800
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Supplementary Table S6a: Objective response rate (ORR) in the 95 NSCLC patients from the UCLA cohort that had at least 1 set of thyroid values obtained on trial available for analysis stratified by the presence or absence of an abnormal TSH value of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0741487249363b84abb94c1d858556e5
https://doi.org/10.1158/2326-6066.22539791.v1
https://doi.org/10.1158/2326-6066.22539791.v1
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Supplementary Table S5a: Cox proportional hazards models for progression-free survival (PFS) with number of treatment related select adverse events included as a time-varying covariate. Listed are results from both unadjusted models and adjusted mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234381fa8cc8be89df45a8b7018e3350
https://doi.org/10.1158/2326-6066.22539794
https://doi.org/10.1158/2326-6066.22539794
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Table S1: All adverse events occurring in > 5% of patients in the UCLA NSCLC cohort of 97 patients treated on KEYNOTE-001.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baeaa313f1b9c131cb725f937dd061e2
https://doi.org/10.1158/2326-6066.22539806
https://doi.org/10.1158/2326-6066.22539806
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Supplementary Table 4a: Objective response rate (ORR), progression-free survival (PFS), and overall survival stratified by the incidence of a grade 2 or higher treatment related AE (trAE) or a trAE of varying degrees of attribution (possible or proba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5096851865145880c9cc3f13b08776c9
https://doi.org/10.1158/2326-6066.22539797.v1
https://doi.org/10.1158/2326-6066.22539797.v1
Autor:
Edward B. Garon, David Elashoff, Narek Shaverdian, Sitaram Vangala, John Madrigal, Caitlin Marx, Danielle Nameth, Natalie Chong, Nima Moghadam, Jaime Hunt, Krikor Bornazyan, Phillip Abarca, Melody Mendenhall, Blanca Ledezma, Jordan McKenzie, Courtney Wells, Marshall L. Spiegel, Carlos Adame, Paulina Linares, Karolyn Morris, Ariana Hardy, James Carroll, Brian Wolf, Jonathan W. Goldman, D. Andrew Tucker, Aaron Lisberg
Supplementary Figure S1A-B. ORR, PFS, and OS analysis for UCLA NSCLC cohort of KEYNOTE-001 trial. ORR, PFS, and OS for all 97 patients in the UCLA cohort of the KEYNOTE-001 trial stratified by the occurrence of a (A) treatment related adverse event (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8972dcb7a51dd9176c099dad2f45cc85
https://doi.org/10.1158/2326-6066.22539809
https://doi.org/10.1158/2326-6066.22539809
Autor:
Blanca Ledezma
Publikováno v:
Oncology Nursing Forum. 36:97-104
Purpose/objectives To discuss the response patterns and side effects related to ipilimumab, a new immunotherapeutic agent under investigation in the treatment of advanced melanoma and other malignancies. Data sources Published articles, abstracts, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0b7044f11dedb3581a0b1386ddd155
https://doi.org/10.1188/09.onf.97-104
https://doi.org/10.1188/09.onf.97-104
Autor:
Melody A. Mendenhall, Jamie Hunt, Ariana Hardy, Krikor Bornazyan, James Carroll, Carlos Adame, Sina Famenini, Jordan Mckenzie, Jonathan W. Goldman, Paulina Linares, Phillip A. Abarca, Marshall Spiegel, Karolyn Morris, Brian R. Wolf, Blanca Ledezma, Aaron Lisberg, Courtney Wells, Jennifer L. Strunck, D. Andrew Tucker
Publikováno v:
Journal of Thoracic Oncology. 12:S1328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da952e2b2029e54c3982034b67d04b35
https://doi.org/10.1016/j.jtho.2016.11.1879
https://doi.org/10.1016/j.jtho.2016.11.1879