Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes

Autor: Quintín Rascón-Cruz, Edward A. Espinoza-Sánchez, Tania S. Siqueiros-Cendón, Sayuri I. Nakamura-Bencomo, Sigifredo Arévalo-Gallegos, Blanca F. Iglesias-Figueroa

Publikováno v: Molecules, Vol 26, Iss 1, p 205 (2021)

Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathog

Externí odkaz: https://doaj.org/article/7d3c87e512474a8e87cb667917a9ff78

Transient expression of a green fluorescent protein in tobacco and maize chloroplast

Autor: Edward A. Espinoza-Sánchez, Tania Siqueiros-Cendón, Héctor Lugo-Aguilar, Gerardo Armando Aguado-Santacruz, Quintín Rascón-Cruz, Hugo Varela-Rodríguez, Blanca F. Iglesias-Figueroa, Sigifredo Arévalo-Gallegos

Publikováno v: Electronic Journal of Biotechnology, Vol 45, Iss, Pp 1-9 (2020)

Background Maize is one of the most important crops worldwide and has been a target of nuclear-based transformation biotechnology to improve it and satisfy the food demand of the ever-growing global population. However, the maize plastid transformati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c06f3e711c752ac1da00aeb58439e8
http://www.sciencedirect.com/science/article/pii/S0717345820300087

Lactoferrin as a nutraceutical protein from milk, an overview

Autor: Blanca F. Iglesias-Figueroa, Edward A. Espinoza-Sánchez, Quintín Rascón-Cruz, Tania Siqueiros-Cendón

Publikováno v: International Dairy Journal. 89:37-41

Lactoferrin, a non-haeme iron-binding glycoprotein, known as the red fraction of milk, has been recently called a nutraceutical protein. Lactoferrin protein participates in some immunological processes and has an antimicrobial response against a broa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9197aa65931d1f7c3bbeafb566c5be1a
https://doi.org/10.1016/j.idairyj.2018.09.004

Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities

Autor: Blanca F. Iglesias-Figueroa, Quintín Rascón-Cruz, Sigifredo Arévalo-Gallegos, Elisa Robles-Escajeda, Tania Siqueiros-Cendón, Armando Varela-Ramirez, Renato J. Aguilera, Denisse A. Gutierrez, Sayuri I. Nakamura-Bencomo, Edward A. Espinoza-Sánchez

Publikováno v: Invest New Drugs

Lactoferrin has gained extensive attention due to its ample biological properties. In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad97972b7a6e3850a2a5a14832f47bc
https://pubmed.ncbi.nlm.nih.gov/33063290

High-Level Expression of Recombinant Bovine Lactoferrin in Pichia pastoris with Antimicrobial Activity

Autor: Norberto Valdiviezo-Godina, Quintín Rascón-Cruz, Tania Siqueiros-Cendón, Sugey Ramona Sinagawa-García, Blanca F. Iglesias-Figueroa, Sigifredo Arévalo-Gallegos

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 6, p 902 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 6; Pages: 902

In this study, bovine lactoferrin (bLf), an iron-binding glycoprotein considered an important nutraceutical protein because of its several properties, was expressed in Pichia pastoris KM71-H under AOX1 promoter control, using pJ902 as the recombinant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c85bbee2d25eaf6280c67fe53fefaf
https://doi.org/10.3390/ijms17060902