How reliably can algorithms identify eosinophilic asthma phenotypes using non‐invasive biomarkers?

Autor: Diana Betancor, José María Olaguibel, José Manuel Rodrigo‐Muñoz, Ebymar Arismendi, Pilar Barranco, Blanca Barroso, Irina Bobolea, Blanca Cárdaba, María Jesús Cruz, Elena Curto, Victoria DelPozo, Francisco‐Javier González‐Barcala, Carlos Martínez‐Rivera, Joaquim Mullol, Xavier Muñoz, Cesar Picado, Vicente Plaza, Santiago Quirce, Manuel Jorge Rial, Lorena Soto, Antonio Valero, Marcela Valverde‐Monge, Joaquin Sastre

Publikováno v: Clinical and Translational Allergy, Vol 12, Iss 8, Pp n/a-n/a (2022)

Abstract Background and Aims Asthma is a heterogeneous respiratory disease that encompasses different inflammatory and functional endophenotypes. Many non‐invasive biomarkers has been investigated to its pathobiology. Heany et al proposed a clinica

Externí odkaz: https://doaj.org/article/49b9fd54170149758cffdf23b373060c

Prioritizing Molecular Biomarkers in Asthma and Respiratory Allergy Using Systems Biology

Autor: Lucía Cremades-Jimeno, María Ángeles de Pedro, María López-Ramos, Joaquín Sastre, Pablo Mínguez, Ignacio Mahillo Fernández, Selene Baos, Blanca Cárdaba

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Highly prevalent respiratory diseases such as asthma and allergy remain a pressing health challenge. Currently, there is an unmet need for precise diagnostic tools capable of predicting the great heterogeneity of these illnesses. In a previous study

Externí odkaz: https://doaj.org/article/97fde5e7cda64fd3ac8250be915370f6

Abstracts from the 3rd International Severe Asthma Forum (ISAF)

Autor: M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw, Ana R. Sousa, Louise J. Fleming, Graham Roberts, Ioannis Pandis, Aruna T. Bansal, Julie Corfield, Scott Wagers, Ratko Djukanovic, Kian Fan Chung, Peter J. Sterk, Jorgen Vestbo, Stephen J. Fowler, S. J. Tebbutt, A. Singh, C. P. Shannon, Y. W. Kim, C. X. Yang, G. M. Gauvreau, J. M. Fitzgerald, L. P. Boulet, P. M. O’Byrne, N. Begley, A. Loudon, D. W. Ray, Selene Baos, Lucía Cremades, David Calzada, Carlos Lahoz, Blanca Cárdaba, Kewal Asosingh, Chris Lauruschkat, Kimberly Queisser, Nicholas Wanner, Kelly Weiss, Weiling Xu, Serpil Erzurum, Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Carolea Logun, Sara Alsaaty, Rosemarie Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron Armando, Edward Dennis, Stewart Levine, James Shelhamer, Kilyong Choi, Snezhina Lazova, Penka Perenovska, Dimitrinka Miteva, Stamatios Priftis, Guergana Petrova, Vassil Yablanski, Evgeni Vlaev, Hristina Rafailova, Takashi Kumae, L. J. Holmes, J. Yorke, D. M. Ryan, Sasawan Chinratanapisit, Khlongtip Matchimmadamrong, Jitladda Deerojanawong, Wissaroot Karoonboonyanan, Paskorn Sritipsukho, Vania Youroukova, Denitsa Dimitrova, Yanina Slavova, Spaska Lesichkova, Iren Tzocheva, Snezhana Parina, Svetla Angelova, Neli Korsun, Mihai Craiu, Iustina Violeta Stan, Matea Deliu, Tolga Yavuz, Matthew Sperrin, Umit M. Sahiner, Danielle Belgrave, Cansin Sackesen Sackesen, Ömer Kalayci, Petar Velikov, Tsvetelina Velikova, Ekaterina Ivanova-Todorova, Kalina Tumangelova-Yuzeir, Dobroslav Kyurkchiev, Spyridon Megremis, Bede Constantinides, Alexandros Georgios Sotiropoulos, Paraskevi Xepapadaki, David Robertson, Nikolaos Papadopoulos, Maxim Wilkinson, Craig Portsmouth, David Ray, Royston Goodacre, Anna Valerieva, Irina Bobolea, Daiana Guillén Vera, Gabriel Gonzalez-Salazar, Carlos Melero Moreno, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, R. Wang, I. Satia, R. Niven, J. A. Smith, T. Southworth, J. Plumb, V. Gupta, J. Pearson, I. Ramis, M. D. Lehner, M. Miralpeix, D. Singh, Imran Satia, Mark Woodhead, Paul O’Byrne, Jaclyn Ann Smith, Cecilia Forss, Peter Cook, Sheila Brown, Freya Svedberg, Katherine Stephenson, Margherita Bertuzzi, Elaine Bignell, Malin Enerbäck, Danen Cunoosamy, Andrew Macdonald, Caini Liu, Liang Zhu, Kiochi Fukuda, Cunjin Zhang, Suidong Ouyang, Xing Chen, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li, Marie-Chantal Larose, Anne-Sophie Archambault, Véronique Provost, Jamila Chakir, Michel Laviolette, Nicolas Flamand, Nicola Logan, Dominik Ruckerl, Judith E. Allen, Tara E. Sutherland, E. Hamelmann, C. Vogelberg, S. Goldstein, G. E. Azzi, M. Engel, R. Sigmund, S. J. Szefler, Raquel Mesquita, Luis Coentrão, Rui Veiga, José-Artur Paiva, Roberto Roncon-Albuquerque, Wendy Vargas Porras, Ana González Moreno, Jesus Macías Iglesias, Gustavo Córdova Ramos, Yesenia Peña Acevedo, Miguel Angel Tejedor Alonso, Maria Del Mar Moro Moro, Irena Krcmova, Jakub Novosad, Nicola Alexander Hanania, Marc Massanari, Heike Hecker, Eric Kassel, Craig Laforce, Kathy Rickard, Sanne Snelder, Gert-Jan Braunstahl, T. L. Jones, D. Neville, E. R. Heiden, E. Lanning, T. Brown, H. Rupani, K. S. Babu, A. J. Chauhan, M. Y. Eldegeir, A. A. Chapman, M. Ferwana, M. Caldron

Publikováno v: Clinical and Translational Allergy, Vol 7, Iss S2, Pp 1-17 (2017)

Externí odkaz: https://doaj.org/article/8aa220adbd1b41528cac7a760f22478f

Discriminatory Molecular Biomarkers of Allergic and Nonallergic Asthma and Its Severity

Autor: Selene Baos, David Calzada, Lucía Cremades-Jimeno, MªÁngeles de Pedro, Joaquín Sastre, César Picado, Joaquín Quiralte, Fernando Florido, Carlos Lahoz, Blanca Cárdaba

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Asthma is a complex disease comprising various phenotypes and endotypes, all of which still need solid biomarkers for accurate classification. In a previous study, we defined specific genes related to asthma and respiratory allergy by studying the ex

Externí odkaz: https://doaj.org/article/9794e29bafc6474cbcdeadece5b56955

Peptide Allergen Immunotherapy: A New Perspective in Olive-Pollen Allergy

Autor: David Calzada, Lucía Cremades-Jimeno, María López-Ramos, Blanca Cárdaba

Publikováno v: Pharmaceutics, Vol 13, Iss 7, p 1007 (2021)

Allergic diseases are highly prevalent disorders, mainly in industrialized countries where they constitute a high global health problem. Allergy is defined as an immune response “shifted toward a type 2 inflammation” induced by the interaction be

Externí odkaz: https://doaj.org/article/6950bdde1d0f4c7b83290795b00bfad6