Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Blake Watkins"'
Publikováno v:
European Journal of Organic Chemistry. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a6f0826bac2a15435ff65c035aa821
https://doi.org/10.1002/ejoc.202200191
https://doi.org/10.1002/ejoc.202200191
Autor:
E. Blake Watkins, Amarender Goud Burra, Dilipkumar Uredi, Damoder Reddy Motati, J. Phillip Bowen, Frank R. Fronczek, Clint R. Smith
Publikováno v:
Organic Chemistry Frontiers. 7:1095-1106
A highly efficient, site-selective, visible light-accelerated, remote C–H halogenation of unsymmetrical aromatic bisamides/amidoesters has been developed. Unprecedented selectivity was realized in this C–H functionalization reaction. The N,N′-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da19f36b126c8dadaa4f678ea8d8c840
https://doi.org/10.1039/c9qo01508f
https://doi.org/10.1039/c9qo01508f
Publikováno v:
The Journal of organic chemistry. 86(24)
Herein, we report a one-pot, three-component method for the preparation of 3-substituted pyridines and carbolines via copper-free, palladium-catalyzed Sonogashira cross-coupling with aryl iodides, followed by 6π-aza cyclization. This arylation cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fe14fbde5502c87a29e087a52f10a2
https://pubmed.ncbi.nlm.nih.gov/34846892
https://pubmed.ncbi.nlm.nih.gov/34846892
Publikováno v:
Current Topics in Medicinal Chemistry. 19:1650-1675
Human immunodeficiency virus type-1 (HIV-1) is the causative agent responsible for the acquired immunodeficiency syndrome (AIDS) pandemic. More than 60 million infections and 25 million deaths have occurred since AIDS was first identified in the earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f9652030f077f65c2398892cddbe2c
https://doi.org/10.2174/1568026619666190717163959
https://doi.org/10.2174/1568026619666190717163959
Publikováno v:
Chemical Communications. 55:3270-3273
A simple and modular one-step synthesis of diversely substituted pyridines from readily available α,β-unsaturated carbonyl compounds and propargylic amines has been developed. The present protocol has a broad substrate scope and allows access to mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c43a5f4562c005c10b2b2c43507580
https://doi.org/10.1039/c9cc01097a
https://doi.org/10.1039/c9cc01097a
Autor:
Amol A. Kulkarni, Ayyiliath M. Sajith, Kathy K. Griendling, M. Damoder Reddy, Qian Xu, Osman F. Güner, E. Blake Watkins, Dilbi Hussein, J. Phillip Bowen, David I. Brown, Bernard Lassègue
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:989-998
NADPH oxidases (Nox enzymes) are critical mediators of both physiologic and pathophysiologic processes. Nox enzymes catalyze NADPH-dependent generation of reactive oxygen species (ROS), including superoxide and hydrogen peroxide. Until recently, Nox4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa644877c37782a9dc84fdd2af54248e
https://doi.org/10.1016/j.bmc.2017.12.023
https://doi.org/10.1016/j.bmc.2017.12.023
Publikováno v:
Journal of Natural Products. 80:2561-2565
Natural products with heteroaromatic cores are ample and widespread in nature, with many compounds exhibiting promising therapeutic properties. (+)-Armillariol C (1a) is a furan-based natural product isolated from Armillaria species. Herein, we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d49731314b0a56e5606ddba43e01ec1
https://doi.org/10.1021/acs.jnatprod.7b00484
https://doi.org/10.1021/acs.jnatprod.7b00484
Metal-catalyzed, bidentate directing group-assisted, C–H activation and functionalization have expanded exponentially in the past few years and provides numerous opportunities in the synthesis of a range of substrates in a straightforward and step-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe90187b1c0a48fb6e925546dfa117d7
https://doi.org/10.1016/b978-0-12-817901-7.00004-6
https://doi.org/10.1016/b978-0-12-817901-7.00004-6
Autor:
J. Phillip Bowen, Amol A. Kulkarni, Osman F. Güner, Bernard Lassègue, Kathy K. Griendling, E. Blake Watkins
Publikováno v:
2018 Medicinal Chemistry Reviews ISBN: 9780996293266
2018 Medicinal Chemistry Reviews
2018 Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f02a832e02de0ef8c15ce49d09ace8f
https://doi.org/10.29200/acsmedchemrev-v53.ch8
https://doi.org/10.29200/acsmedchemrev-v53.ch8
Publikováno v:
Organic Letters. 18:5620-5623
Rh-catalyzed, chelation-induced, C-5 regioselective C–H functionalization of 8-amidoquinolines with a range of N-Boc aminals is reported for the first time. The addition of in situ generated imines to C(sp2)–H bonds afforded branched amines in go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab1ae9b5f9a8d94266361c9d2bbd8f9
https://doi.org/10.1021/acs.orglett.6b02848
https://doi.org/10.1021/acs.orglett.6b02848