Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Blake T. Enyart"'
Autor:
Marcello Rubino, Joshua G. Travers, Alaina L. Headrick, Blake T. Enyart, Madeleine E. Lemieux, Maria A. Cavasin, Jessica A. Schwisow, Elizabeth J. Hardy, Keenan J. Kaltenbacher, Marina B. Felisbino, Eric Jonas, Amrut V. Ambardekar, Michael R. Bristow, Keith A. Koch, Timothy A. McKinsey
Publikováno v:
Circulation Research. 132:10-29
Background: Organ fibrosis due to excessive production of extracellular matrix by resident fibroblasts is estimated to contribute to >45% of deaths in the Western world, including those due to cardiovascular diseases such as heart failure. Here, we s
Autor:
Qiong Zhou, Raphael A. Nemenoff, Mary C.M. Weiser-Evans, Sizhao Lu, Allison M. Dubner, Keith A. Koch, Austin J Jolly, Daniel V. LaBarbera, Blake T. Enyart, Linfeng Li, Keith A. Strand, Karen S. Moulton, Marie F Mutryn
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Our recent work demonstrates that PTEN (phosphatase and tensin homolog) is an important regulator of smooth muscle cell (SMC) phenotype. SMC-specific PTEN deletion promotes spontaneous vascular remodeling and PTEN loss correlates with incr