Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Blake S Moses"'
Autor:
Allison Bruce, Rebecca Evans, Ryan Mezan, Lin Shi, Blake S Moses, Karen H Martin, Laura F Gibson, Yong Yang
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140506 (2015)
Acute lymphoblastic leukemia (ALL) initiates and progresses in the bone marrow, and as such, the marrow microenvironment is a critical regulatory component in development of this cancer. However, ALL studies were conducted mainly on flat plastic subs
Externí odkaz:
https://doaj.org/article/88a95ad7fdfe4f8dacabe847a30a18dd
Autor:
Amanda B. Kagan, Blake S. Moses, Bryan T. Mott, Ganesha Rai, Nicole M. Anders, Michelle A. Rudek, Curt I. Civin
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Acute myeloid leukemia (AML) remains a devastating disease, with low cure rates despite intensive standard chemotherapy regimens. In the past decade, targeted antileukemic drugs have emerged from research efforts. Nevertheless, targeted therapies are
Externí odkaz:
https://doaj.org/article/2cf6566fed2a4ca3b0fec12ce23940fd
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
S2A, REH leukemic cells have overexpressed p27 protein compared to empty vector control. S2B, an increase in viability was observed in REH cells overexpressing p27 compared to empty vector control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039b7355d19e4a9c2371968fdea2a569
https://doi.org/10.1158/1541-7786.22514092
https://doi.org/10.1158/1541-7786.22514092
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Excel sheet showing mean signal intensities and p-values of SUP-B15 ALL cells cultured in media only or co-cultured with BMSC. Statistics were done as follows: Data were analyzed by first subtracting the background and then normalizing the signals us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f4c4d69be602a607f93ad03b0a5640
https://doi.org/10.1158/1541-7786.22514089
https://doi.org/10.1158/1541-7786.22514089
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Consistent with p27 two other validated miR-221/222 target genes which have been previously shown to play a role in cellular quiescence and survival, PTEN and CDKN1C (p57), were assessed in leukemic cells under conditions mentioned above. S1A,B, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cdac0af735c96284c88621853e00d6
https://doi.org/10.1158/1541-7786.22514095
https://doi.org/10.1158/1541-7786.22514095
Autor:
Laura F. Gibson, Michael D. Craig, Ivan Martinez, Debbie Piktel, William L. Slone, Rebecca Evans, Blake S. Moses
Excel sheet showing mean signal intensities and p-values of SUP-B15 ALL cells cultured in media only or co-cultured with HOB. Statistics were done as follows: Data were analyzed by first subtracting the background and then normalizing the signals usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a2ae256ffa5d39dc2aa943ec98c296
https://doi.org/10.1158/1541-7786.22514086.v1
https://doi.org/10.1158/1541-7786.22514086.v1
Autor:
Blake S Moses, Chris Materna, Remya Nathan, Tandicka Nurse, Keith Babbs, Claire Tseng, Ffolliott Fisher, Jasbir Seehra, Jenn Lachey
Publikováno v:
Blood. 140:9763-9764
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb1d94f26d90f4e983e3cb13b7c1619
https://doi.org/10.1182/blood-2022-169360
https://doi.org/10.1182/blood-2022-169360
Autor:
Maria R. Baer, Amol C. Shetty, Elizabeth T. Chang, Sandrine Niyongere, Erin T. Strovel, Rena G. Lapidus, Ronald B. Gartenhaus, Kayla M. Tighe, Bandish Kapadia, Brandon Carter-Cooper, Ashkan Emadi, Anup Mahurkar, Farin Kamangar, Binny Bhandary, Dominique R Bollino, Xinrong Ma, Eun Yong Choi, Curt I. Civin, Blake S. Moses, Hannah Kaizer
Publikováno v:
Leukemia. 35:1907-1924
Complex karyotype acute myeloid leukemia (CK-AML) has a dismal outcome with current treatments, underscoring the need for new therapies. Here, we report synergistic anti-leukemic activity of the BCL-2 inhibitor venetoclax (Ven) and the asparaginase f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4f447e32bc885894d0581f7dc94883d
https://doi.org/10.1038/s41375-020-01080-6
https://doi.org/10.1038/s41375-020-01080-6
Autor:
Ashkan Emadi, Tami J. Kingsbury, Samantha McCullough, Søren M. Bentzen, Michelle A. Rudek, Jeffrey W. Tyner, MinJung Kim, Bryan T. Mott, Jennifer M. Fox, Rena G. Lapidus, Blake S. Moses, Curt I. Civin
Publikováno v:
Blood Adv
Artemisinins are active against human leukemia cell lines and have low clinical toxicity in worldwide use as antimalarials. Because multiagent combination regimens are necessary to cure fully evolved leukemias, we sought to leverage our previous find
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fe546e2ae9a535af0e4d4ef178c45a
https://europepmc.org/articles/PMC7876886/
https://europepmc.org/articles/PMC7876886/
Autor:
Ashkan, Emadi, Bandish, Kapadia, Dominique, Bollino, Binny, Bhandary, Maria R, Baer, Sandrine, Niyongere, Erin T, Strovel, Hannah, Kaizer, Elizabeth, Chang, Eun Yong, Choi, Xinrong, Ma, Kayla M, Tighe, Brandon, Carter-Cooper, Blake S, Moses, Curt I, Civin, Anup, Mahurkar, Amol C, Shetty, Ronald B, Gartenhaus, Farin, Kamangar, Rena G, Lapidus
Publikováno v:
Leukemia. 35(7)
Complex karyotype acute myeloid leukemia (CK-AML) has a dismal outcome with current treatments, underscoring the need for new therapies. Here, we report synergistic anti-leukemic activity of the BCL-2 inhibitor venetoclax (Ven) and the asparaginase f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27c5b282ff67e6db1f75b329001536c8
https://pubmed.ncbi.nlm.nih.gov/33199836
https://pubmed.ncbi.nlm.nih.gov/33199836