Výsledky vyhledávání - "Blake Broaten"

IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice

Autor: Karsten Sauer, Lana Schaffer, Luise Westernberg, Stephanie Rigaud, Sabine Siegemund, Blake Broaten, Claire Conche, Steven R. Head

Publikováno v: Blood. 125:2786-2797

Tight regulation of hematopoietic stem cell (HSC) homeostasis ensures lifelong hematopoiesis and prevents blood cancers. The mechanisms balancing HSC quiescence with expansion and differentiation into hematopoietic progenitors are incompletely unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede8696cf945ad77c48dcab5c0d88327
https://doi.org/10.1182/blood-2014-06-583187

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A novel peptide pool with broad infectious antigen and MHC coverage for use as a positive stimulation control or as a means to elicit general T-cell responsiveness

Autor: Aaron Castro, Pavlo Holenya, Maren Eckey, Marco Schulz, Holger Wenschuh, Ulf Reimer, Tatjana Tech, Kam Chan, Ramesh Janani, Blake Broaten, Florian Kern

Publikováno v: The Journal of Immunology. 200:120.15-120.15

T-cell activation assays such as Elispot or Intracellular Cytokine Staining (ICS) require appropriate positive stimulation controls. Compared with conventional assay controls based on polyclonal stimulation (e.g. PHA/Ionomycin), peptide pools have th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bece857f9f4f091563077f9981eda53
https://doi.org/10.4049/jimmunol.200.supp.120.15

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