Near-infrared 808 nm light boosts complex IV-dependent respiration and rescues a Parkinson-related pink1 model.

Autor: Melissa Vos, Blaise Lovisa, Ann Geens, Vanessa A Morais, Georges Wagnières, Hubert van den Bergh, Alec Ginggen, Bart De Strooper, Yanik Tardy, Patrik Verstreken

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78562 (2013)

Mitochondrial electron transport chain (ETC) defects are observed in Parkinson's disease (PD) patients and in PD fly- and mouse-models; however it remains to be tested if acute improvement of ETC function alleviates PD-relevant defects. We tested the

Externí odkaz: https://doaj.org/article/6d0b93c3ff114760812c7c0d1c08a002

Autofluorescence bronchoscopy: quantification of inter-patient variations of fluorescence intensity

Autor: Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht, Blaise Lovisa

Autofluorescence (AF) from bronchial tissue is increasingly used for the endoscopic detection of early bronchial neoplasia. Several imaging systems are commercially available, all detecting the absolute or relative AF intensity and/or spectral contra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736ce1587840f32f41ec1ec5bc8a9958
http://doc.rero.ch/record/317683/files/10103_2007_Article_518.pdf

Optical properties of the deep brain in the red and NIR: changes observed under in-vivo, post-mortem, frozen and formalin-fixated conditions

Autor: Olivier Seydoux, M. Zellweger, Matthias Haenggi, Andreas Pitzschke, Yanik Tardy, Markus Florian Oertel, Blaise Lovisa, Georges Wagnières, M. Pfleiderer

Publikováno v: Medical Laser Applications and Laser-Tissue Interactions VII.

Photobiomodulation (PBM) is a promising approach to treat Parkinson's disease (PD) symptoms in cellular or animal models. Unfortunately, little information is available on the optical parameters playing a role in the light dosimetry during PBM. We co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b359b0de770ca8d8973df8c27d762198
https://doi.org/10.1117/12.2183687

Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions

Autor: Olivier Seydoux, Markus Florian Oertel, Blaise Lovisa, Yanik Tardy, Matthias Haenggi, Andreas Pitzschke, Matthieu Zellweger, Georges Wagnières

Publikováno v: Journal of biomedical optics

The outcome of light-based therapeutic approaches depends on light propagation in biological tissues, which is governed by their optical properties. The objective of this study was to quantify optical properties of brain tissue in vivo and postmortem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fec532ddf4dbf3ff305f10510b063d
https://pubmed.ncbi.nlm.nih.gov/25706688

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion

Autor: Hubert van den Bergh, Arjan W. Griffioen, Jean-Pierre Ballini, Blaise Lovisa, Judy R. van Beijnum, Andrea Weiss, Patrycja Nowak-Sliwinska, Tse J. Wong

Publikováno v: Journal of Cellular and Molecular Medicine, 16(7), 1553-1562. Wiley-Blackwell
Journal of Cellular and Molecular Medicine, vol. 16, no. 7, pp. 1553-1562
Journal of Cellular and Molecular Medicine
Nowak-Sliwinska, P, Weiss, A, van Beijnum, J R, Wong, T J, Ballini, J P, Lovisa, B, van den Bergh, H & Griffioen, A W 2012, ' Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion ', Journal of Cellular and Molecular Medicine, vol. 16, no. 7, pp. 1553-1562 . https://doi.org/10.1111/j.1582-4934.2011.01440.x

Targeted angiostatic therapy receives major attention for the treatment of cancer and exudative age-related macular degeneration (AMD). Photodynamic therapy (PDT) has been used as an effective clinical approach for these diseases. Since PDT can cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3280b9e4d6f29fa1a2a16159d22832a5
https://research.vumc.nl/en/publications/6eb3924b-b837-4ddb-9ba3-9004480ed94b