Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Blaise, Dumat"'
Autor:
Christopher P. Lawson, Anders F. Füchtbauer, Moa S. Wranne, Tristan Giraud, Thomas Floyd, Blaise Dumat, Nicolai K. Andersen, Afaf H. El-Sagheer, Tom Brown, Henrik Gradén, L. Marcus Wilhelmsson, Morten Grøtli
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Fluorescent base analogues (FBAs) have emerged as a powerful class of molecular reporters of location and environment for nucleic acids. In our overall mission to develop bright and useful FBAs for all natural nucleobases, herein we describe
Externí odkaz:
https://doaj.org/article/91467726e61f4f76abb1785ce4f6f727
Autor:
Sylvestre P. J. T. Bachollet, Yuriy Shpinov, Fanny Broch, Hela Benaissa, Arnaud Gautier, Nicolas Pietrancosta, Jean-Maurice Mallet, Blaise Dumat
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, In press, ⟨10.1039/d1ob02394b⟩
Organic & Biomolecular Chemistry, In press, ⟨10.1039/d1ob02394b⟩
International audience; We report the development of HaloTag fluorogens based on dipolar flexible molecular rotor structures. By modulating the electron donating and withdrawing groups, we have tuned the absorption and emission wavelengths to design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca177eebe15e1f3156a586faf77d2d5
https://doi.org/10.1039/d1ob02394b
https://doi.org/10.1039/d1ob02394b
Publikováno v:
Chemical Communications. 58:6594-6597
The fluorogenic activation of a calcium molecular probe via reaction with HaloTag yields a fluorescent AND logic gate enabling selective and wash-free calcium imaging in genetically-defined organelles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5311040a8067e1866c8878ed1f401f0d
https://doi.org/10.1039/d2cc01792j
https://doi.org/10.1039/d2cc01792j
Autor:
Blaise Dumat, Nicolas Pietrancosta, Sylvestre P. J. T. Bachollet, Cyril Addi, Jean-Maurice Mallet
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2020, ⟨10.1002/chem.202002911⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2020, ⟨10.1002/chem.202002911⟩
International audience; Fluorogenic probes are important tools to image proteins with high contrast and no wash protocols. In this work, we rationally designed and synthesized a small set of four protein fluorogens with red or near-infrared emission.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0ec127eb2c15f435861979f9c7f81d
https://doi.org/10.1002/chem.202002911
https://doi.org/10.1002/chem.202002911
We introduce a strategy for the fluorogenic and genetic targeting of a calcium sensor by combining a protein fluorogen with the BAPTA sensing group. The resulting dual-input probe acts like a fluorescent AND logic gate with a Ca2+-sensitive red emiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c697d98d64b25354e9d07c274b7b04
https://doi.org/10.26434/chemrxiv-2022-g64d8
https://doi.org/10.26434/chemrxiv-2022-g64d8
Autor:
Pascal Matton, Blaise Dumat, Laurent Cattiaux, Léa Pinon, Lorraine Montel, Jean-Maurice Mallet, Jacques Fattaccioli
Publikováno v:
ACS Applied Bio Materials
ACS Applied Bio Materials, 2019, ⟨10.1021/acsabm.9b00793⟩
ACS Applied Bio Materials, ACS Publications, 2019, ⟨10.1021/acsabm.9b00793⟩
ACS Applied Bio Materials, 2019, ⟨10.1021/acsabm.9b00793⟩
ACS Applied Bio Materials, ACS Publications, 2019, ⟨10.1021/acsabm.9b00793⟩
International audience; In this work we report on the development of mannose-coated fluorescent lipid microparticles to study the role of C-type lectin membrane receptor in phagocytosis. The micrometric droplets of soybean oil in water emulsion were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec7ff664f1fba4e117413760a469313
https://doi.org/10.1021/acsabm.9b00793
https://doi.org/10.1021/acsabm.9b00793
Autor:
Moa S, Wranne, Anders Foller, Füchtbauer, Blaise, Dumat, Mattias, Bood, Afaf H, El-Sagheer, Tom, Brown, Henrik, Gradén, Morten, Grøtli, L Marcus, Wilhelmsson
Publikováno v:
Journal of the American Chemical Society. 139(27)
Förster resonance energy transfer (FRET) using fluorescent base analogues is a powerful means of obtaining high-resolution nucleic acid structure and dynamics information that favorably complements techniques such as NMR and X-ray crystallography. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68e8590b5a4dd97f5fd9c107dcb04ac0
https://pubmed.ncbi.nlm.nih.gov/28613885
https://pubmed.ncbi.nlm.nih.gov/28613885
Autor:
Patrick Tauc, Nathalie Gagey-Eilstein, Blaise Dumat, Marie-Paule Teulade-Fichou, Houcine Bougherara, Florence Mahuteau-Betzer, Stéphanie Bury-Moné, Etienne Henry, Eric Deprez, Frédéric Subra, Rahima Chennoufi
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep21458⟩
Molecular Imaging
Scientific Reports (2045-2322) (Nature Publishing Group), 2016-03, Vol. 6, N. 21458, P. 12p.
Scientific Reports, Nature Publishing Group, 2016, 6 (1), ⟨10.1038/srep21458⟩
Molecular Imaging
Scientific Reports (2045-2322) (Nature Publishing Group), 2016-03, Vol. 6, N. 21458, P. 12p.
Photodynamic therapy (PDT) leads to cell death by using a combination of a photosensitizer and an external light source for the production of lethal doses of reactive oxygen species (ROS). Since a major limitation of PDT is the poor penetration of UV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5325e5052226be4e50c4ab8e37ad92
https://hal.archives-ouvertes.fr/hal-02350542
https://hal.archives-ouvertes.fr/hal-02350542
Autor:
Blaise Dumat, Guillaume Bordeau, Céline Fiorini-Debuisschert, Fabrice Charra, Germain Metgé, Marie-Paule Teulade-Fichou, M. Bombled, Nicolas Saettel, Elodie Faurel-Paul, Florence Mahuteau-Betzer
Publikováno v:
Biochimie. 93:1209-1218
Herein we report on the synthesis and DNA recognition properties of a series of three N-phenyl carbazole-based light-up probes initially designed for two-photon absorption. The vinylic derivatives (Cbz-2Py, Cbz-3Py) display strong fluorescence enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a8a8cdf871bb296d7d9573cd8e0086
https://doi.org/10.1016/j.biochi.2011.05.035
https://doi.org/10.1016/j.biochi.2011.05.035
Autor:
Christopher P. Lawson, Søren Preus, Marcus Wilhelmsson, Blaise Dumat, Henrik Gradén, Mattias Bood, Anders Foller Larsen, Morten Grøtli, Moa Sandberg Wranne
Publikováno v:
Scientific Reports
Larsen, A F, Dumat, B, Wranne, M S, Lawson, C P, Preus, S, Bood, M, Graden, H, Wilhelmsson, L M & Grøtli, M 2015, ' Development of bright fluorescent quadracyclic adenine analogues : TDDFT-calculation supported rational design ', Scientific Reports, vol. 5, 12653 . https://doi.org/10.1038/srep12653
Larsen, A F, Dumat, B, Wranne, M S, Lawson, C P, Preus, S, Bood, M, Graden, H, Wilhelmsson, L M & Grøtli, M 2015, ' Development of bright fluorescent quadracyclic adenine analogues : TDDFT-calculation supported rational design ', Scientific Reports, vol. 5, 12653 . https://doi.org/10.1038/srep12653
Fluorescent base analogues (FBAs) comprise a family of increasingly important molecules for the investigation of nucleic acid structure and dynamics. We recently reported the quantum chemical calculation supported development of four microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3280bf914a243c3bddebc59a3ed25376
https://doi.org/10.1038/srep12653
https://doi.org/10.1038/srep12653