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pro vyhledávání: '"Blair A.M. Walker"'
Publikováno v:
Annals of the New York Academy of Sciences. 603:108-118
There is an increasing body of evidence suggesting that nucleotides such as ATP can serve as important extracellular factors to bring about significant functional changes in phagocytic cells. For instance, ATP and its analogues (for example, adenosin
Autor:
Peter A. Ward, Blair A.M. Walker
Publikováno v:
Biological signals. 1(5)
The priming response is a common feature for almost all agents which activate neutrophils. The priming response is associated with a number of events such as degranulation, receptor upregulation, increases in [Ca2+]i and the production of lipid secon
Publikováno v:
Journal of leukocyte biology. 50(6)
Although rat peritoneal neutrophils in the presence of cytochalasin B demonstrate superoxide (O2-) responses to the chemotactic peptide N'-formyl-met-leu-phe (FMLP), neither elicited rat peritoneal macrophages nor rat alveolar macrophages show an O2-
Publikováno v:
Biochemical and Biophysical Research Communications. 154:746-751
In formyl peptide stimulated human neutrophils the enhancement of O2 • responses by ATP and ATPγS requires extracellular calcium. In contrast, the inhibitory effects of adenosine are independent of a calcium requirement. Rates of O2 • generation