Výsledky vyhledávání - "Bladder remodeling"

Akademický článek

Single‐cell transcriptomics reveal the remodeling landscape of bladder in patients with obstruction‐induced detrusor underactivity

Autor: Jiawei Chen, Liao Peng, Guo Chen, Yuanzhuo Chen, Xiao Zeng, Jie Zhang, Chi Zhang, Hong Shen, Banghua Liao, Deyi Luo

Publikováno v: MedComm, Vol 5, Iss 3, Pp n/a-n/a (2024)

Abstract Detrusor underactivity (DUA) is a common and thorny problem in urology, which severely impairs patients’ bladder function and quality of life. However, its underlying pathophysiological mechanism remains unclear. Hence, we sequenced 69,973

Externí odkaz: https://doaj.org/article/30a6837977614ba0ae6b1e6bd360e3f1

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Akademický článek

Advances in molecular mechanism of bladder detrusor dysfunction

Autor: LIU Sheng-lai, TIAN Da-wei, WU Chang-li

Publikováno v: Jichu yixue yu linchuang, Vol 42, Iss 10, Pp 1606-1610 (2022)

Bladder outlet obstruction (BOO) increases micturition resistance and prolongs the duration of intravesical hypertension. The intravesical pressure overloads the hydrostatic pressure and mechanical tensile force of detrusor,which triggers the cascade

Externí odkaz: https://doaj.org/article/5d55527da34342e79ce1d8f8b6184dd8

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Akademický článek

YAP-mediated mechanotransduction in urinary bladder remodeling: Based on RNA-seq and CUT&Tag

Autor: Xingpeng Di, Liyuan Xiang, Zhongyu Jian

Publikováno v: Frontiers in Genetics, Vol 14 (2023)

Yes-associated protein (YAP) is an important transcriptional coactivator binding to transcriptional factors that engage in many downstream gene transcription. Partial bladder outlet obstruction (pBOO) causes a massive burden to patients and finally l

Externí odkaz: https://doaj.org/article/11d802c5d90d4c37a905e2956444f606

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Akademický článek

RETRACTED: Survivin knockdown alleviates pathological hydrostatic pressure-induced bladder smooth muscle cell dysfunction and BOO-induced bladder remodeling via autophagy

Autor: Guo Chen, Shuang Chen, Xingpeng Di, Shengyin He, Yugao Liu, Rui Qu, Yi Luo, Yuebai Liu, Luo Yang

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Aim: Bladder outlet obstruction (BOO) leads to bladder wall remodeling accompanying the progression from inflammation to fibrosis where pathological hydrostatic pressure (HP)-induced alteration of bladder smooth muscle cells (BSMCs) hypertrophic and

Externí odkaz: https://doaj.org/article/bde0897cf7b24bfcbe7fe9b480554fe5

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Akademický článek

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Akademický článek

Progressive bladder remodeling due to bladder outlet obstruction: a systematic review of morphological and molecular evidences in humans

Autor: Ferdinando Fusco, Massimiliano Creta, Cosimo De Nunzio, Valerio Iacovelli, Francesco Mangiapia, Vincenzo Li Marzi, Enrico Finazzi Agrò

Publikováno v: BMC Urology, Vol 18, Iss 1, Pp 1-11 (2018)

Abstract Background Bladder outlet obstruction is a common urological condition. We aimed to summarize available evidences about bladder outlet obstruction-induced molecular and morphological alterations occurring in human bladder. Methods We perform

Externí odkaz: https://doaj.org/article/edc79746bae74889b37a35bbc9173b42

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Molecular Characterization of Non-Neurogenic and Neurogenic Lower Urinary Tract Dysfunction (LUTD) in SCI-Induced and Partial Bladder Outlet Obstruction Mouse Models

Autor: von Siebenthal, Michelle, Akshay, Akshay, Besic, Mustafa, Schneider, Marc P, Hashemi Gheinani, Ali, Burkhard, Fiona C, Monastyrskaya, Katia

Publikováno v: von Siebenthal, Michelle; Akshay, Akshay; Besic, Mustafa; Schneider, Marc P; Hashemi Gheinani, Ali; Burkhard, Fiona C; Monastyrskaya, Katia (2023). Molecular Characterization of Non-Neurogenic and Neurogenic Lower Urinary Tract Dysfunction (LUTD) in SCI-Induced and Partial Bladder Outlet Obstruction Mouse Models. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032451
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2451

We examined bladder function following spinal cord injury (SCI) by repeated urodynamic investigation (UDI), including external urethral sphincter (EUS) electromyography (EMG) in awake restrained mice and correlated micturition parameters to gene expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704a74f28a61a6549c757478b0a80b6a

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