LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency.

Autor: O'Connor MN; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Kallenberg DM; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Camilli C; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Pilotti C; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Dritsoula A; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Jackstadt R; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK., Bowers CE; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Watson HA; Division of Infection and Immunity, School of Medicine and Systems Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK., Alatsatianos M; Division of Infection and Immunity, School of Medicine and Systems Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK., Ohme J; Division of Infection and Immunity, School of Medicine and Systems Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK., Dowsett L; Institute of Ophthalmology, University College London, London SE5 8BN, UK., George J; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Blackburn JWD; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Wang X; Institute of Ophthalmology, University College London, London SE5 8BN, UK., Singhal M; Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany; Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Augustin HG; Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany; Department of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Ager A; Division of Infection and Immunity, School of Medicine and Systems Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK., Moss SE; Institute of Ophthalmology, University College London, London SE5 8BN, UK. Electronic address: s.moss@ucl.ac.uk., Greenwood J; Institute of Ophthalmology, University College London, London SE5 8BN, UK. Electronic address: j.greenwood@ucl.ac.uk.

Publikováno v: Med (New York, N.Y.) [Med] 2021 Nov 12; Vol. 2 (11), pp. 1231-1252.e10. Date of Electronic Publication: 2021 Nov 03.

Antagonistic Coevolution of MER Tyrosine Kinase Expression and Function.

Autor: Evans AL; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Blackburn JWD; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Taruc K; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Kipp A; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Dirk BS; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Hunt NR; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Barr SD; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Dikeakos JD; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada., Heit B; Department of Microbiology and Immunology and the Centre for Human Immunology, The University of Western Ontario, London, Canada.

Publikováno v: Molecular biology and evolution [Mol Biol Evol] 2017 Jul 01; Vol. 34 (7), pp. 1613-1628.