Tandem amplification of SCCmec can drive high level methicillin resistance in MRSA

Autor: Gallagher, Laura A., Coughlan, Simone, Black, Nikki S., Lalor, Pierce, Waters, Elaine M., Wee, Bryan, Watson, Mick, Downing, Tim, Fitzgerald, J. Ross, Fleming, Gerard T. A., O'gara, James P.

Publikováno v: Gallagher, L A, Coughlan, S, Black, N S, Lalor, P, Waters, E M, Wee, B, Watson, M, Downing, T, Fitzgerald, J R, Fleming, G T A & O'gara, J P 2017, ' Tandem amplification of SCCmec can drive high level methicillin resistance in MRSA ', Antimicrobial Agents and Chemotherapy, vol. 61, no. 9, e00869-17 . https://doi.org/10.1128/AAC.00869-17

Hospital-associated methicillin-resistant Staphylococcus aureus strains typically express high level, homogenous (HoR) β-lactam resistance, whereas community-associated MRSA (CA-MRSA) more commonly express low level heterogeneous (HeR) resistance. E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::6ded6e4dad500086329fd5b1f333f870
https://hdl.handle.net/20.500.11820/4ab6da16-c5dd-45e3-914c-a43f4b579f3b

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Redeploying β-Lactam Antibiotics as a Novel Antivirulence Strategy for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections.

Autor: Waters, Elaine M., Rudkin, Justine K., Coughlan, Simone, Clair, Geremy C., Adkins, Joshua N., Gore, Suzanna, Guoqing Xia, Black, Nikki S., Downing, Tim, O'Neill, Eoghan, Kadioglu, Aras, P. O'Gara, James, Xia, Guoqing, O'Gara, James P

Publikováno v: Journal of Infectious Diseases; Jan2017, Vol. 215 Issue 1, p80-87, 8p