Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bjoern von Eyss"'
Autor:
Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Bjoern Von Eyss, Vilja Eskelinen, Pauliina Munne, Anni I. Nieminen, Timo Otonkoski, Julia Schüler, Teemu D. Laajala, Tero Aittokallio, Harri Sihto, Johanna Mattson, Päivi Heikkilä, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha Klefström
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Elevated MYC levels can sensitize tumor cells to apoptosis. In this study, the authors demonstrate that AMPK activation and BCL-2/BCL-XL inhibition have a synergistic effect on apoptosis, and that together with anti PD-1 therapy they can suppress Myc
Externí odkaz:
https://doaj.org/article/d3f1f919795e44fe8702e5ba84a712b6
Autor:
Heidi M. Haikala, Johanna M. Anttila, Elsa Marques, Tiina Raatikainen, Mette Ilander, Henna Hakanen, Hanna Ala-Hongisto, Mariel Savelius, Diego Balboa, Bjoern Von Eyss, Vilja Eskelinen, Pauliina Munne, Anni I. Nieminen, Timo Otonkoski, Julia Schüler, Teemu D. Laajala, Tero Aittokallio, Harri Sihto, Johanna Mattson, Päivi Heikkilä, Marjut Leidenius, Heikki Joensuu, Satu Mustjoki, Panu Kovanen, Martin Eilers, Joel D. Leverson, Juha Klefström
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in Fig. 7. In panel b, the survival curves were shifted relative to the y axis. This error has been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/be938228d9c14a09b1d43012150cc2cd
Publikováno v:
Molecular Cancer Research. 18:A10-A10
During aging, several tissues display a progressive functional decline potentially leading to malfunction of whole organ systems. This phenomenon can also be observed in the hematopoietic system since aged hematopoietic stem cells (HSCs) display seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::212589d6efe360ed1fc24e8d7d128e92
https://doi.org/10.1158/1557-3125.hippo19-a10
https://doi.org/10.1158/1557-3125.hippo19-a10
Autor:
Richard Treisman, Bjoern von Eyss, Cyril Esnault, Andreas Rosenwald, Elmar Wolf, Heidi M. Haikala, Martin Eilers, Katrin E. Wiese, Juha Klefström
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2015, 34 (11), pp.1554-71. ⟨10.15252/embj.201490467⟩
EMBO Journal, EMBO Press, 2015, 34 (11), pp.1554-71. ⟨10.15252/embj.201490467⟩
International audience; Oncogenic levels of Myc expression sensitize cells to multiple apoptotic stimuli, and this protects long-lived organisms from cancer development. How cells discriminate physiological from supraphysiological levels of Myc is la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee95b938c5f6f46608acb567f6da1a7c
https://doi.org/10.15252/embj.201490467
https://doi.org/10.15252/embj.201490467
Autor:
Johanna Mattson, Martin Eilers, Harri Sihto, Henna Hakanen, Heikki Joensuu, Päivi Heikkilä, Mette Ilander, Joel D. Leverson, Timo Otonkoski, Teemu D. Laajala, Panu E. Kovanen, Johanna M. Anttila, Bjoern von Eyss, Vilja Eskelinen, Tiina Raatikainen, Elsa Marques, Julia Schüler, Diego Balboa, Tero Aittokallio, Mariel Savelius, Pauliina Munne, Hanna Ala-Hongisto, Juha Klefström, Marjut Leidenius, Heidi M. Haikala, Anni I. Nieminen, Satu Mustjoki
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
The original version of this Article contained an error in Fig. 7. In panel b, the survival curves were shifted relative to the y axis. This error has been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4171f32836a7ac070a8cc9874928bc48
https://doaj.org/article/be938228d9c14a09b1d43012150cc2cd
https://doaj.org/article/be938228d9c14a09b1d43012150cc2cd
Publikováno v:
Molecular Cancer Research. 13:B19-B19
For the maintenance of a given tissue it is absolutely critical to balance proliferation and differentiation of stem cells, progenitor cells and terminally differentiated cells. Perturbations of these finely tuned processes can lead to various diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4536f0d713c198a5c39fbc2b8f031850
https://doi.org/10.1158/1557-3125.myc15-b19
https://doi.org/10.1158/1557-3125.myc15-b19