Výsledky vyhledávání - "Bjoern Moosmann"

Development of a non-radioactive mass spectrometry-based binding assay at the μ-opioid receptor and its application for the determination of the binding affinities of 17 opiates/opioids as well as of the designer opioid isotonitazene and five further 2-benzylbenzimidazoles

Autor: Madeleine Ramona Volz, Bjoern Moosmann

Publikováno v: Analytica chimica acta. 1219

Radioactive ligand binding assays are the most commonly applied method for the determination of binding affinities of compounds at a particular receptor. While they are highly sensitive and high-throughput capable they come with major disadvantages d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60db67c2e514c672ff46cb526336138d
https://pubmed.ncbi.nlm.nih.gov/35715126

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5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA

Autor: Verena Angerer, Bjoern Moosmann, Volker Auwärter, Florian Franz, Philippe Bisel

Publikováno v: Forensic Toxicology

Purpose In recent years e-liquids used in electronic cigarettes have become an attractive alternative to smoking tobacco. A new trend is the use of e-liquids containing synthetic cannabinoids (SCs) instead of smoking cannabis or herbal mixtures laced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb2b6acc299590e21ae0ab23cf5147e
https://doi.org/10.1007/s11419-018-0451-8

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Detection of the recently emerged synthetic cannabinoid 5F-MDMB-PICA in ‘legal high’ products and human urine samples

Autor: Lukas Mogler, Verena Angerer, Michael Kassiou, Mitchell Longworth, Daniel Rentsch, Georg Weinfurtner, Florian Franz, Volker Auwärter, Samuel D. Banister, Bjoern Moosmann

Publikováno v: Drug Testing and Analysis. 10:196-205

Indole or indazole-based synthetic cannabinoids (SCs) bearing substituents derived from valine or tert-leucine are frequently abused new psychoactive substances (NPS). The emergence of 5F-MDMB-PICA (methyl N-{[1-(5-fluoropentyl)-1H-indol-3-yl]carbony

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4cd603ab698f8efcabcce59081ae7d4
https://doi.org/10.1002/dta.2201

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Flubromazolam - Basic pharmacokinetic evaluation of a highly potent designer benzodiazepine

Autor: Laura M. Huppertz, Bjoern Moosmann, Volker Auwärter

Publikováno v: Drug Testing and Analysis. 10:206-211

Since their first appearance on the Internet in 2012, designer benzodiazepines established as an additional, quickly growing compound class among new psychoactive substances. Data regarding pharmacokinetic parameters, metabolism, and detectability fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60c3678ee762b5961a625b47c3c74cea
https://doi.org/10.1002/dta.2203

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Characterization andin vitrophase I microsomal metabolism of designer benzodiazepines - an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam and nitrazolam

Autor: Florian Franz, Philippe Bisel, Bjoern Moosmann, Volker Auwärter, Laura M. Huppertz

Publikováno v: Journal of Mass Spectrometry. 51:1080-1089

Designer benzodiazepines represent an emerging class of new psychoactive substances. While other classes of new psychoactive substances such as cannabinoid receptor agonists and designer stimulants are mainly consumed for hedonistic reasons, designer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e584eeb4538d19d0d1cb9baf5ee1043
https://doi.org/10.1002/jms.3840

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Phase I metabolism of the highly potent synthetic cannabinoid MDMB-CHMICA and detection in human urine samples

Autor: Bjoern Moosmann, Florian Franz, Volker Auwärter, Verena Angerer

Publikováno v: Drug Testing and Analysis. 9:744-753

Among the recently emerged synthetic cannabinoids, MDMB-CHMICA (methyl N-{[1-(cyclohexylmethyl)-1H-indol-3-yl]carbonyl}-3-methylvalinate) shows an extraordinarily high prevalence in intoxication cases, necessitating analytical methods capable of dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dde1f9572c2ded00ce2bddac2b294338
https://doi.org/10.1002/dta.2049

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