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Autor:
Abeer Hanafy, Alper Okyar, Gül Baktir, Hilde Spahn-Langguth, Cornelia Dressler, Bjoern Lemmer
Publikováno v:
Chronobiology International. 29:443-453
The circadian timing system (CTS) governs the 24-h rhythm of the organism and, hence, also main pathways responsible for drug pharmacokinetics. P-glycoprotein (P-gp) is a drug transporter that plays a pivotal role in drug absorption, distribution, an
Autor:
Bjoern Lemmer, Reinhard Feneberg
Publikováno v:
Chronobiology International. 21:521-538
Hypertension and noninsulin-dependent diabetes mellitus are usually associated with marked glucose intolerance. Hypertensive and even nonhypertensive diabetic individuals display disturbances of the normal circadian blood pressure rhythm. However, li
Autor:
Bjoern Lemmer, Grit Heise, Brigitte Peters, Karl Otto Dubowy, Axel Rentzsch, Brigitte Stiller, Petra Boettler, Alfred Hager, Julia Lemmer, Titus Kuehne
Publikováno v:
Clinical research in cardiology : official journal of the German Cardiac Society. 100(4)
We investigated whether a correlation exists between biomarkers of the neurohumoral system and clinical markers in grown-up patients with congenital heart disease (GUCH) and right ventricular function. Prospective, cross-sectional, multicenter study
Autor:
Hans-Joerg Hippe, Maike Knorr, Norbert Frey, Christina Grundt, Benedikt Brors, Bjoern Lemmer, Hugo A. Katus, Mirko Voelkers, Patrick Most, Mark Luedde, Derk Frank, Ulrich Flögel, Claude Antony, Uta Haselmann, J. Schrader
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 87(4)
Hypertrophic cardiomyopathy (HCM) is associated with cardiac hypertrophy, diastolic dysfunction, and sudden death. Recently, it has been suggested that inefficient energy utilization could be a common molecular pathway of HCM-related mutations. We ha
Publikováno v:
Advanced drug delivery reviews. 59(9-10)
Study of the chronobiology of allergic rhinitis (AR) and bronchial asthma (BA) and the chronopharmacology and chronotherapy of the medications used in their treatment began five decades ago. AR is an inflammatory disease of the upper airway tissue wi
Autor:
Emmanuel Boselli, Lionel Bouvet, Dominique Chassard, F. Boiste, Bjoern Lemmer, Steven L. Shafer, Bernard Allaouchiche
Publikováno v:
Obstetric Anesthesia Digest. 31:230-231
Background The duration of analgesia from epidural administration of local anesthetics to parturients has been shown to follow a rhythmic pattern according to the time of drug administration. We studied whether there was a similar pattern after intra
Autor:
Jochen Schrader, Francesco Portaluppi, Gudrun Nold, Stephan Lueders, Bjoern Lemmer, Roberto Manfredini
Publikováno v:
American Journal of Hypertension. 15:A109
NORMALISATION OF NON-DIPPING BLOOD PRESSURE PROFILE BY AMLODIPINE AFTER SINGLE MORNING OR EVENING DOSING Bjoern Lemmer, Stephan Lueders, Gudrun Nold, Jochen Schrader, Roberto Manfredini, Francesco Portaluppi. Institute of Pharmacology & Toxicology, U
Lemmer/Brune: Das Lehrbuch der klinischen Pharmakologie, jetzt in der 13. Auflage! - prüfungsrelevantes Wissen prägnant und übersichtlich, - praxisorientierte Darstellung der Pharmakotherapie bei allen GK-relevanten, häufigen Krankheitsbilder
Publikováno v:
Journal of Bone and Mineral Research. 19:168-169