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Autor:
Gabriele Stephan, Caroline Wilde, Norbert Sträter, Niklas Ravn-Boess, Dimitris G. Placantonakis, Giselle R. Wiggin, Devin Bready, Ines Liebscher, Torsten Schöneberg, Joshua D. Frenster, Jordan Wilcox, Bjoern Kieslich
SUMMARYGPR133 (ADGRD1), an adhesion G protein-coupled receptor (GPCR), is necessary for growth of glioblastoma (GBM), a brain malignancy. The extracellular N-terminus of GPR133 is thought to be autoproteolytically cleaved into an N-terminal and a C-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444de5b90da68873a1b5b185058e3f33
https://doi.org/10.1101/2020.12.08.415398
https://doi.org/10.1101/2020.12.08.415398
Autor:
Dimitris G. Placantonakis, Jordan Wilcox, Joshua D. Frenster, Devin Bready, Torsten Schöneberg, Caroline Wilde, Niklas Ravn-Boess, Ines Liebscher, Giselle R. Wiggin, Bjoern Kieslich, Gabriele Stephan, Norbert Sträter
Publikováno v:
The Journal of Biological Chemistry
GPR133 (ADGRD1), an adhesion G protein–coupled receptor (GPCR) whose canonical signaling activates GαS-mediated generation of cytosolic cAMP, has been shown to be necessary for the growth of glioblastoma (GBM), a brain malignancy. The extracellula