Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bjoern Bartels"'
Autor:
Michael Reutlinger, Georg Schmitt, Roland Jakob-Roetne, Anja Limberg, Hasane Ratni, Werner Neidhart, Solen Pichereau, Caterina Bissantz, Karlheinz Baumann, Rosa-Maria Rodriguez-Sarmiento, Mingqiu Lu, Bjoern Bartels, Irene Gerlach, André Alker, Eric Zhang, Chen Weichun
Publikováno v:
ACS Med Chem Lett
[Image: see text] γ-Secretase (GS) is a key target for the potential treatment of Alzheimer’s disease. While inhibiting GS led to serious side effects, its modulation holds a lot of potential to deliver a safe treatment. Herein, we report the disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794566175e39407157febc7ccb1d38a9
https://doi.org/10.1021/acsmedchemlett.0c00109
https://doi.org/10.1021/acsmedchemlett.0c00109
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:970-976
A scalable 5-step synthesis of the diazacarbazole derivative 1 used as tau PET tracer precursor is reported. Key features of this synthesis include a Buchwald-Hartwig amination, a Pd catalyzed CH activation and a Suzuki-Miyaura cross-coupling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38113eab8b54092d1cfce0e5acb11b83
https://doi.org/10.1016/j.bmc.2017.10.007
https://doi.org/10.1016/j.bmc.2017.10.007
ChemInform Abstract: Cu-Catalyzed Aerobic Oxidative Cyclization of Guanidylpyridines and Derivatives
Autor:
Serena Fantasia, Bjoern Bartels, Nicolas Gaeng, Philipp Cueni, Conor Gordon Bolas, Andrada Stefania Trita
Publikováno v:
ChemInform. 46
A simple and highly efficient system produces a series of 2-amino-[1,2,4]triazolo[1,5-a]pyridine structures and analogues such as (X) and (XII).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::549145031b5217cb312c1032ada08d20
https://doi.org/10.1002/chin.201524178
https://doi.org/10.1002/chin.201524178
Publikováno v:
ResearcherID
Monodentate phosphorus amidites derived from 2,2′-binaphthol and a variety of chiral amines were employed as ligands in IrI-catalysed allylic alkylations of unsymmetrically substituted allylic acetates. The enantio- and regioselectivities of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d562ee2782df2ccd4210c4ad28c85f
https://doi.org/10.1002/ejoc.200390162
https://doi.org/10.1002/ejoc.200390162
Publikováno v:
ResearcherID
Ir-catalysed allylic alkylations of enantiomerically enriched monosubstituted allylic acetates proceed with up to 87% retention of configuration using P(OPh)3 as ligand. High regio- and enantioselectivity of up to 86% ee in asymmetric allylic alkylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7f3772bc1eaefc75d7cbb32e170b9d
https://doi.org/10.1002/1099-0682(200210)2002:10<2569::aid-ejic2569>3.0.co
https://doi.org/10.1002/1099-0682(200210)2002:10<2569::aid-ejic2569>3.0.co
Autor:
Andrada Stefania Trita, Nicolas Gaeng, Serena Fantasia, Bjoern Bartels, Conor Gordon Bolas, Philipp Cueni
Publikováno v:
The Journal of organic chemistry. 80(2)
A new method for the straightforward synthesis of 2-amino-[1,2,4]triazolo[1,5-a]pyridines and derivatives is presented. The target products are synthesized in high yields from guanidylpyridines and analogues via copper-catalyzed N–N coupling. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f481e403f2e2ccda153d03310bab24aa
https://pubmed.ncbi.nlm.nih.gov/25495477
https://pubmed.ncbi.nlm.nih.gov/25495477
Supply chains for electronic products are primarily driven by consumer electronics. Every year new mobile phones, computers and gaming consoles are introduced, driving the continued applicability of Moore's law. The semiconductor manufacturing indust
Autor:
Stuart Warren, Matthew G. Russell, Jonathan Clayden, Bjoern Bartels, Adam Nelson, Concepcion Gonzalez Martin
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1807-1822
Some hydrogen, carbon, silicon, sulfur, nitrogen and oxygen nucleophiles react diastereoselectively with γ-oxygenated chiral vinyl phosphine oxides to give β-substituted phosphine oxides. Lithium N-benzyl-α-methylbenzylamide adds to prochiral viny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98f53297aca4bed2a05423416e91b8d
https://doi.org/10.1039/a902414j
https://doi.org/10.1039/a902414j
Publikováno v:
Strategies to the Prediction, Mitigation and Management of Product Obsolescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43307908f1bb7fa98000cdab20df74d5
https://doi.org/10.1002/9781118275474.ch7
https://doi.org/10.1002/9781118275474.ch7
Publikováno v:
Strategies to the Prediction, Mitigation and Management of Product Obsolescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd8c32cc4466d616f5bfee46d5cdc26
https://doi.org/10.1002/9781118275474.ch5
https://doi.org/10.1002/9781118275474.ch5