Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins

Autor: Preisler, Sarah Spruce, Wiuf, Anders Drabaek, Friis, Marc, Kjaergaard, Lasse, Hurd, Molly, Becares, Eva Ramos, Nurup, Casper Normann, Bjoerkskov, Frederik Bühring, Szathmáry, Zsófia, Gourdon, Pontus Emanuel, Calloe, Kirstine, Klaerke, Dan A., Gotfryd, Kamil, Pedersen, Per Amstrup

Publikováno v: Preisler, S S, Wiuf, A D, Friis, M, Kjaergaard, L, Hurd, M, Becares, E R, Nurup, C N, Bjoerkskov, F B, Szathmáry, Z, Gourdon, P E, Calloe, K, Klaerke, D A, Gotfryd, K & Pedersen, P A 2021, ' Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins ', Current research in structural biology, vol. 3, pp. 51-71 . https://doi.org/10.1016/j.crstbi.2021.02.001

Integral membrane proteins (IMPs) constitute ~30% of all proteins encoded by the genome of any organism and Escherichia coli remains the first-choice host for recombinant production of prokaryotic IMPs. However, the expression levels of prokaryotic I

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https://curis.ku.dk/portal/da/publications/saccharomyces-cerevisiae-as-a-superior-host-for-overproduction-of-prokaryotic-integral-membrane-proteins(81f3107e-054c-46cf-9df4-8191c4bed27b).html