Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Björn Hackanson"'
Autor:
Christoph Rummelt, Olga Grishina, Claudia Schmoor, Martina Crysandt, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Gerhard Heil, Carsten Müller-Tidow, Wolfram Brugger, Andrea Kündgen, Maike de Wit, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Jürgen Krauter, Gesine Bug, Haifa Kathrin Al-Ali, Ralph Wäsch, Heiko Becker, Annette M. May, Justus Duyster, Björn Hackanson, Arnold Ganser, Hartmut Döhner, Michael Lübbert
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/3448ad0c720c4bd583057eb97a440fb5
Autor:
Tobias Dechow, Jorge Riera‐Knorrenschild, Björn Hackanson, Jan Janssen, Holger Schulz, Marco Chiabudini, Ludwig Fischer von Weikersthal, Stephan Budweiser, Axel Nacke, Dagmar Taeuscher, Manfred Welslau, Karin Potthoff
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 8127-8137 (2021)
Abstract Background Platinum‐based chemotherapy remains a first‐line standard of care for approximately 30% of patients with non‐small cell lung cancer (NSCLC) not harboring a druggable alteration. Favorable efficacy and safety of the nab‐pac
Externí odkaz:
https://doaj.org/article/5b6b2c18b24b4eb19418ef882658d450
Autor:
Julian Riba, Nathalie Renz, Christoph Niemöller, Sabine Bleul, Dietmar Pfeifer, Juliane M Stosch, Klaus H Metzeler, Björn Hackanson, Michael Lübbert, Justus Duyster, Peter Koltay, Roland Zengerle, Rainer Claus, Stefan Zimmermann, Heiko Becker
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163455 (2016)
Intratumoral genetic heterogeneity may impact disease outcome. Gold standard for dissecting clonal heterogeneity are single-cell analyses. Here, we present an efficient workflow based on an advanced Single-Cell Printer (SCP) device for the study of g
Externí odkaz:
https://doaj.org/article/8d6448eb2ab344218de60403e980e9a8
Autor:
Alexander Krohn, Theresa Ahrens, Arzu Yalcin, Till Plönes, Julius Wehrle, Sanaz Taromi, Stefan Wollner, Marie Follo, Thomas Brabletz, Sendurai A Mani, Rainer Claus, Björn Hackanson, Meike Burger
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100249 (2014)
Small Cell Lung Cancer (SCLC) is a specific subtype of lung cancer presenting as highly metastatic disease with extremely poor prognosis. Despite responding initially well to chemo- or radiotherapy, SCLC almost invariably relapses and develops resist
Externí odkaz:
https://doaj.org/article/1c3b2b8d31454e7bb69a19dfbd931a51
Autor:
Nadja Blagitko-Dorfs, Yi Jiang, Jesús Duque-Afonso, Jan Hiller, Arzu Yalcin, Gabriele Greve, Mahmoud Abdelkarim, Björn Hackanson, Michael Lübbert
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75258 (2013)
All-trans retinoic acid (ATRA) has only limited single agent activity in AML without the PML-RARα fusion (non-M3 AML). In search of a sensitizing strategy to overcome this relative ATRA resistance, we investigated the potency of the HDAC class-I sel
Externí odkaz:
https://doaj.org/article/376223d26eb8438d9a063edac2c39c55
Autor:
Michael Lübbert, Björn H. Rüter, Rainer Claus, Claudia Schmoor, Mathias Schmid, Ulrich Germing, Andrea Kuendgen, Volker Rethwisch, Arnold Ganser, Uwe Platzbecker, Oliver Galm, Wolfram Brugger, Gerhard Heil, Björn Hackanson, Barbara Deschler, Konstanze Döhner, Anne Hagemeijer, Pierre W. Wijermans, Hartmut Döhner
Publikováno v:
Haematologica, Vol 97, Iss 3 (2012)
Background The treatment of acute myeloid leukemia of older, medically non-fit patients still poses a highly unmet clinical need, and only few large, prospective studies have been performed in this setting. Given the established activity of hypomethy
Externí odkaz:
https://doaj.org/article/f169518690794aaab52479f591519dbb
Autor:
Gabriele Greve, Geoffroy Andrieux, Pascal Schlosser, Nadja Blagitko-Dorfs, Usama-Ur Rehman, Tobias Ma, Dietmar Pfeifer, Gerhard Heil, Andreas Neubauer, Jürgen Krauter, Michael Heuser, Helmut R. Salih, Konstanze Döhner, Hartmut Döhner, Björn Hackanson, Melanie Boerries, Michael Lübbert
Publikováno v:
Leukemia. 37:1018-1027
Despite routine use of DNA-hypomethylating agents (HMAs) in AML/MDS therapy, their mechanisms of action are not yet unraveled. Pleiotropic effects of HMAs include global methylome and transcriptome changes. We asked whether in blasts and T-cells from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b5a8f4e01d28508897d6192d74def0
https://doi.org/10.1038/s41375-023-01876-2
https://doi.org/10.1038/s41375-023-01876-2
Autor:
Tobias Dechow, Jorge Riera‐Knorrenschild, Björn Hackanson, Jan Janssen, Holger Schulz, Ursula Oppermann, Marco Chiabudini, Ludwig Fischer von Weikersthal, Stephan Budweiser, Axel Nacke, Dagmar Taeuscher, Manfred Welslau, Karin Potthoff
Publikováno v:
International Journal of Cancer. 153:141-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d66c57c784f50aeed18c3e26fa82752d
https://doi.org/10.1002/ijc.34467
https://doi.org/10.1002/ijc.34467
Autor:
Christoph Plass, Charis Eng, Frank Weber, David E. Schuller, James C. Lang, Carl D. Morrison, Laura T. Smith, Björn Hackanson, Kristi L. Bennett
Supplementary Table 4 from Tumor Suppressor Activity of CCAAT/Enhancer Binding Protein α Is Epigenetically Down-regulated in Head and Neck Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6ebbd7c54b06e122e8e9e80a97297c
https://doi.org/10.1158/0008-5472.22368287
https://doi.org/10.1158/0008-5472.22368287
Autor:
Christoph Plass, Charis Eng, Frank Weber, David E. Schuller, James C. Lang, Carl D. Morrison, Laura T. Smith, Björn Hackanson, Kristi L. Bennett
Supplementary Table 1 from Tumor Suppressor Activity of CCAAT/Enhancer Binding Protein α Is Epigenetically Down-regulated in Head and Neck Squamous Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8e5092ee0cb83e251a215653938b94
https://doi.org/10.1158/0008-5472.22368296.v1
https://doi.org/10.1158/0008-5472.22368296.v1