Glepaglutide, a novel glucagon-like peptide-2 agonist, has anti-inflammatory and mucosal regenerative effects in an experimental model of inflammatory bowel disease in rats

Autor: Jolanta Skarbaliene, Jesper Mosolff Mathiesen, Bjarne Due Larsen, Christian Thorkildsen, Yvette Miata Petersen

Publikováno v: BMC Gastroenterology, Vol 23, Iss 1, Pp 1-9 (2023)

Abstract Background Glucagon-like peptide-2 (GLP-2) enhances intestinal repair and attenuates inflammation in preclinical inflammatory bowel disease (IBD) models, making GLP-2 analogues attractive candidates for IBD therapy. Glepaglutide is a long-ac

Externí odkaz: https://doaj.org/article/914d3c0bb5004d14a880381ddc36d5ff

Applications of SNP-based apple pedigree identification to regionally specific germplasm collections and breeding programs

Autor: Nicholas P. Howard, Caroline Denancé, Bjarne Due Larsen, M. Troggio, James J. Luby, D. C. Albach, M. Ristel, C.E. Durel, Helene Muranty, E. van de Weg

Publikováno v: Acta Horticulturae, 1307, 231-238
Acta Horticulturae
Acta Horticulturae, International Society for Horticultural Science, 2021, Proceedings of the XV EUCARPIA Symposium on Fruit Breeding and Genetics (2019, Prague) (1307), pp.231-238. ⟨10.17660/ActaHortic.2021.1307.36⟩
Acta Horticulturae 1307 (2021)

International audience; A wealth of previously unknown pedigree information has been generated for apple (Malus × domestica) through recent studies and an ongoing pedigree identification project using SNP array data. This information has been postul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb39698e36934ef18de5293c087a899
http://hdl.handle.net/20.500.12278/40282

Genome-Wide association studies in apple reveal loci for aroma volatiles, sugar composition, and harvest Date

Autor: Mikael Agerlin Petersen, Torben Bo Toldam-Andersen, Anne Aae Jeppesen, Kyle M. Gardner, Zoë Migicovsky, Marian Ørgaard, Carsten Pedersen, Bjarne Due Larsen, Sean Myles

Publikováno v: Plant Genome, 12(2)
Plant Genome 12 (2019) 2
Larsen, B, Migicovsky, Z, Jeppesen, A A, Gardner, K M, Toldam-Andersen, T B, Myles, S, Ørgaard, M, Petersen, M A & Pedersen, C 2019, ' Genome-Wide Association Studies in Apple Reveal Loci for Aroma Volatiles, Sugar Composition, and Harvest Date ', The Plant Genome, vol. 12, no. 2, 180104 . https://doi.org/10.3835/plantgenome2018.12.0104
The Plant Genome, Vol 12, Iss 2 (2019)

Understanding the genetic architecture of fruit quality traits is crucial to target breeding of apple (Malus domestica L.) cultivars. We linked genotype and phenotype information by combining genotyping-by-sequencing (GBS) generated single nucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d3f6ba14795c4b0b6ea62206f97c27
https://doi.org/10.3835/plantgenome2018.12.0104

Population structure, relatedness and ploidy levels in an apple gene bank revealed through genotyping-by-sequencing

Autor: Zoë Migicovsky, Carsten Pedersen, Kyle M. Gardner, Sean Myles, Bjarne Due Larsen, Marian Ørgaard, Torben Bo Toldam-Andersen

Publikováno v: Larsen, B, Gardner, K, Pedersen, C, Ørgaard, M, Migicovsky, Z, Myles, S & Toldam-andersen, T B 2018, ' Population structure, relatedness and ploidy levels in an apple gene bank revealed through genotyping-by-sequencing ', PLoS ONE, vol. 13, no. 8, e0201889, pp. 1-14 . https://doi.org/10.1371/journal.pone.0201889
PLoS ONE, Vol 13, Iss 8, p e0201889 (2018)
PLoS ONE

In recent years, new genome-wide marker systems have provided highly informative alternatives to low density marker systems for evaluating plant populations. To date, most apple germplasm collections have been genotyped using low-density markers such

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b338823ea2a2d1bde031c1bd032f6c6
https://curis.ku.dk/ws/files/201003963/file.pdf

Unravelling genetic diversity and cultivar parentage in the Danish apple gene bank collection

Autor: Marian Ørgaard, Bjarne Due Larsen, Torben Bo Toldam-Andersen, Carsten Pedersen

Publikováno v: Tree Genetics & Genomes. 13

Characterization of apple germplasm is important for conservation management and breeding strategies. A set of 448 Malus domestica accessions, primarily of local Danish origin, were genotyped using 15 microsatellite markers. Ploidy levels were determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::169b378162fde3194da8965d1c328416
https://doi.org/10.1007/s11295-016-1087-7