Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bjarne D Larsen"'
Autor:
Yu-Cheng Hsieh, Wan-Hsin Hsieh, Cheng-Hung Li, Ying-Chieh Liao, Jiunn-Cherng Lin, Chi-Jen Weng, Men-Tzung Lo, Ta-Chuan Tuan, Shien-Fong Lin, Hung-I Yeh, Jin-Long Huang, Ketil Haugan, Bjarne D Larsen, Yenn-Jiang Lin, Wei-Wen Lin, Tsu-Juey Wu, Shih-Ann Chen
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228818 (2020)
INTRODUCTION:High beat-to-beat morphological variation (divergence) on the ventricular electrogram during programmed ventricular stimulation (PVS) is associated with increased risk of ventricular fibrillation (VF), with unclear mechanisms. We hypothe
Externí odkaz:
https://doaj.org/article/83e8b9be0534499ca659eeda38f47182
Autor:
Eve-Irene Lepist, Bente Steffansen, Bjarne D. Larsen, Hans Lennernäs, Sven Frokjaer, Mitchell E. Taub
Publikováno v:
European Journal of Pharmaceutical Sciences. 8:67-73
The model prodrug D-Asp(OBzl)-Ala has previously been shown to have affinity and to be transported by the oligopeptide transporter PepT1 expressed in Caco-2 cells. The main objective of the present study was to investigate the aqueous stability of D-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc04539221a2274b5f608199beb96219
https://doi.org/10.1016/s0928-0987(98)00062-1
https://doi.org/10.1016/s0928-0987(98)00062-1
Publikováno v:
European Journal of Pharmaceutical Sciences. 7:317-323
Four N-terminal 4-imidazolidinone prodrugs of Leu-enkephalin are prepared and characterized. Their enzymatic and chemical stability are assessed using high-performance liquid chromatography. The prodrug derivatives are shown to degrade stoichiometric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a1f87a1ad10233cb7b5eae5ab6f996
https://doi.org/10.1016/s0928-0987(98)00044-x
https://doi.org/10.1016/s0928-0987(98)00044-x
Publikováno v:
International Journal of Pharmaceutics. 146:205-212
d -Asp-Ala, a metabolically stable dipeptide, possesses a relatively high affinity for the Caco-2 oligopeptide transporter (IC50 = 5.75 ± 0.09 mM) as demonstrated by its ability to compete with [14c]Gly-Sar in cellular uptake experiments. When the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702557e65c823ece3488bc0354f9424d
https://doi.org/10.1016/s0378-5173(96)04802-8
https://doi.org/10.1016/s0378-5173(96)04802-8
Publikováno v:
International Journal of Pharmaceutics. 136:61-69
Two N-Z-protected dipeptides were N-hydroxymethylated at the C-terminal peptide bond. The stability of the derivatives was investigated in aqueous buffer solutions as a function of pH. The compounds degraded quantitatively to their parent N-Z-protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::528646aba183e7cf11fe3a5e55df1e61
https://doi.org/10.1016/0378-5173(95)04481-7
https://doi.org/10.1016/0378-5173(95)04481-7
Autor:
Giampiero Muccioli, Aderville Cabassi, Lucy Vulchanova, Maureen S. Riedl, Monia Manieri, Andrea Frontini, Antonio Giordano, Saverio Cinti, Paolo Govoni, Gallia Graiani, Federico Quaini, Corrado Ghè, Elena Bresciani, Ilaria Bulgarelli, Antonio Torsello, Vittorio Locatelli, Valentina Sanghez, Bjarne D. Larsen, Jorgen S. Petersen, Paola Palanza
Publikováno v:
Biochemical Journal; Jan2012, Vol. 441 Issue 1, p511-522, 12p